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dys-
comes from Greek, where it means "bad, difficult, or abnormal
dysfunctional
Operating or functioning in an impaired or abnormal way.
dyslexia
A physical interference with the ability to read or to use language.
dyspeptic
Suffering from indigestion; having an irritable temperament
dystrophy
Any of several disorders involving nerves and muscles, such as "muscular dystrophy."