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Types of viruses
Flu
Herpes
Hepatitis A, B, & C
Most antivirals and antibiotics have what SE
GI distress
Anti-viral
Acyclovir
Acyclovir use
to prevent replication for herpes virus
Acyclovir SE
crystalluria
caution w/ electrolyte disorder
Acyclovir caution
nephrotoxicity
seizure disorder
Acyclovir teaching
increase fluid intake
get up slowly (orthostatic htn)
Anti-fungal (local)
Nystatin
Nystatin (topical) use
athlete's foot
Nystatin (oral) use
oral candidiasis (thrush)
vaginal candidiasis (yeast infection)
superficial fungal infections
oral candidiasis (thrush)
vaginal candidiasis (yeast infection)
tinea pedis (athletes foot)
systemic fungal infections
Lungs
CNS
abdomen
Opportunistic fungal infections
immunocompromised patient
superinfection
steroids
chemotherapy
Anti-fungal (systemic)
fluconazole
fluconazole route
Oral, IV, vaginal, topical
fluconazole use
-systemic fungal infections
-immunosuppressed pts to prevent yeast infection
fluconazole nursing interventions
-culture PRIOR to medication
- monitor LFTs
Urinary antiseptic
Nitrofurantoin
Nitrofurantoin use
acute and chronic UTIs
Nitrofurantoin teaching
-Notify MD if there are signs of superinfection
-rinse mouth (stains teeth)
-urine turns rust/brown
Nitrofurantoin SE
turns urine rust/brown
Urinary analgesic
Phenazopyridine
Phenazopyridine use
does not get rid of infection
relieves symptoms
Phenazopyridine SE
red-orange urine and secretions
inherent resistance
Ability of the host to resist the disease independent of antibodies
acquired resistance
bacterial resistance to a drug to which they were previously taking for long periods of time
When should C & S be done?
prior to starting antibiotic
Macrolide antibiotic
Azithromycin
Antacid administration with macrolides
2 hr before or after macrolide dose
Azithromycin use
-STI
-Chlamydia
-when pts are allergic to PCN/cephalosporins
for stronger bacterial infections
Azithromycin SE
blurred vision
headache
drowsiness
fatigue
photosensitivity
Azithromycin ADR
Superinfection
tinnitus
hepatotoxicity (liver)
Azithromycin contraindications
hepatic/renal dysfunction
heart issues
TYLENOL
Azithromycin nursing interventions
monitor for liver enzymes & for s/s of liver issues
Glycopeptide antibiotic
Vancomycin
Vancomycin use
MRSA
serious infections
Vancomycin IV caution
give slowly to prevent redman syndrome
Vancomycin SE
chills
dizziness
GI distress
Thrombophlebitis (central IV)
Vancomycin ADR
nephrotoxic
ototoxic
redman syndrome
redman syndrome SE
rash to face, neck, back and chest
htn
tachycardia
wheezing
sometimes itching
Vancomycin nursing interventions
peak & trough
hearing test
renal test
Tetracycline antibiotic
Doxycycline
Doxycycline use
infections
acne
Doxycycline SE
stomatitis
GI distress
photosensitivity
discoloration of permanent teeth
Doxycycline ADR
superinfection
hepatoxicity
sjs
Doxycycline contraindications
decreases effects of oral contraceptives
children under 8
pregnant women
Doxycycline teaching
-use another form of birth control
-avoid milk, iron, antacids
Aminoglycoside antibiotic
Gentamicin
Gentamicin use
serious infections
Gentamicin SE
ototoxicity
superinfection
nephrotoxicity
Gentamicin nursing interventions
peak and trough
baseline hearing test
Sulfonamides antibiotic
trimethoprim/sulfamethoxazole
Trimethoprim-sulfamethoxazole use
both drugs together cause bacteria resistance to develop much more slowly
-uti
-mrsa
-alternative to penicillin
Trimethoprim-sulfamethoxazole SE
photosensitivity
Trimethoprim-sulfamethoxazole ADR
hypoglycemia
crystalluria
Trimethoprim-sulfamethoxazole caution
diabetes
Trimethoprim-sulfamethoxazole teaching
sun precautions
Trimethoprim-sulfamethoxazole topical use
burns
sometimes skin ulcers
Amoxicillin SE
tongue discoloration
stomatitis
glossitis
Amoxicillin contraindications
allergy to other PCN or cephalosporins
decrease effect with acidic fruits/juices
Penicillin antibiotic
Amoxicillin
Amoxicillin use
bacterial infections
Amoxicillin ADR
C. diff associated diarrhea
Fluoroquinolones antibiotics
Ciprofloxacin
Levofloxacin
Ciprofloxacin & Levofloxacin use
severe infections
Ciprofloxacin & Levofloxacin ADR
SJS
tendon rupture
nephrotoxicity
hepatotoxicity
Antibiotics
Metronidazole
Cephalosporins
Amoxicillin
Azithromycin
Vancomycin
Doxycycline
Gentamicin
Ciprofloxacin
Levofloxacin
Trimethoprim-sulfamethoxazole
Metronidazole teaching
NO alcohol
reaction: facial flushing, sweating, severe HA, slurred speech
Metronidazole use
GI (H. Pylori)
GU (STIs)
Metronidazole SE
Superinfection-(C.diff / thrush)
dark urine
metallic/bitter taste
GI distress
Cephalosporins use
bacterial infections
Cephalosporins SE
GI upset
dizziness/ vertigo
headache
Cephalosporins ADR
superinfection
nephrotoxicity
Cephalosporins teaching
Report symptoms ADR of yeast infection
no citric juices
Cephalosporins administration
IV over 30 mins
IM mixed w/ solution
Gastrointestinal antiemetics
promethazine
ondansetron
metoclopramide
promethazine SE
dizziness
(anticholinergic) DRYYYY
promethazine ADR
EPS
respiratory distress
ondansetron SE
headache
dizziness
metoclopramide MOA
increases GI emptying
metoclopramide use
POST OP
helps with peristalsis
metoclopramide SE
high doses can cause sedation & diarrhea
Gastrointestinal antidiarrheal
diphenoxylate with atropine
diphenoxylate with atropine use
diarrhea
diphenoxylate with atropine MOA
slows gastric motility
diphenoxylate with atropine caution
paralytic ileus with long term use
monitor bowel sounds
Gastrointestinal laxative
Bisacodyl
Bisacodyl use
constipation
Bisacodyl ADR
dependence
hypokalemia
Bisacodyl contraindiciations
if you have an electrolyte imbalance DO NOT GIVE
Bisacodyl nursing interventions
use only as needed with water
Metabolic acidosis
pooping
"pooping out your ass"
Metabolic alkalosis
vomiting
Antiulcers
antacid
famotidine
pantoprazole
sucralfate
Antacid
Magnesium (Mg) hydroxide/aluminum hydroxide
Famotidine (Pepcid) use
treat peptic ulcers & GERD
Famotidine (Pepcid) MOA
reduce gastric acid
Famotidine (Pepcid) contraindications
tale 30 mins before any other drugs
Pantoprazole MOA
reduce gastric acid
Pantoprazole contraindication
Take 30 mins before any other drug