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Hyperemia
increased blood flow in capilllaries of alveolar walls- associated with acute inflammation from infection or irritants
Congestion
stasis of blood in alveolar capillaries
associated with left-sided hear failure
common incidental finding at necropsy
Cardiogenic edema
edema caused by increased pressure in pulmonary vasculature with stasis of blood from left-sided heart failure
1) endothelial damage, 2) altered blood flow, 3) Hypercoagulability
Virchow’s triad- cause of thrombi formation
Ventricular septal defect
congenital
causes overload of right ventricle with blood from the left ventricle
brisket edema
high altitude disease
cattle kept in hypoxic conditions at high altitudes- development of pulmonary hypertension and right sided heart failure
Mannheimia hemolytica
Pasteurella multocida
Actinobacillus pleuropneumonia
3 major bacterial causes of bronchopneumonia
Thoracic empyema
accumulation of purulent exudate and foreign material in thoracic cavity
Acute respiratory distress syndrome
acute pulmonary injury that is an acute interstitial pneumonia
hyaline membrane
condensed fibrin, serum proteins and cell debris that occurs in acute interstitial pneumonia
L-tryptophan
compound converted by ruminal bacteria to 30methylindole during acute bovine pulmonary emphysema and edema
equine herpesvirus 5
causative agent of equine multi nodular pulmonary fibrosis
Bronchointerstitial pneumonia
term used to describe pneumonia when there are features that fit into the two categories
Adenocarcinomas
most common primary neoplasm
Pleural frosting
Uremic mineralization of the pleura
From blood stream
From GIT
Through body wall
From lung itself
Through lymphatics
5 causes of pleuritis
Hydrothorax
Accumulation of edema fluid in thoracic cavity
Chylothorax
Accumulation of lipid-rich lymph in thoracic cavity
Cats
most common species that chylothorax occurs in
Hemothorax
Accumulation of blood in thoracic cavity
Pneumothorax
Influx of air into thoracic cavity
mesotheliomas
Primary tumors of mesothelium
carcinomatosis
carcinomas spreading to other body locations
common in pleural neoplasia
Neuropil
dense network of neural and glial processes found in gray matter
Ischemic cell change
Neurons shrink with hypereosinophilic cytoplasm
glia limitans
Layer of astrocytes on the entire brain and spinal cord
Astrocytosis
swelling and proliferation of astrocytes with mild injury
Glial scar
Dense network of proliferative astrocytic processes
Gitter cells
the cells that are phagocytizing something in the nervous system
they `get really big and have a lot of cytoplasm
Gliosis
Proliferation of glial cells secondary to CNS injury
Pia mater
Arachnoid mater
Dura mater
layers of meninges from inner to outer
Dysraphia
Failure of closure of neural tube during embryonic development
Anencephaly
Complete absence of brain
Prosencephalic hypoplasia
Absence of cerebral hemispheres with varying degrees of brain stem development
Cranium bifidum
Midline bone defect through which meningeal and/or brain tissue may protrude
Meningocele
Meninges only herniate during cranium bifidum or spina bifida
Meningoencephalocele
Meninges and brain herniate during cranium bifidum
Spina bifida
Defect in dorsal vertebral column which spinal meninges or spinal cord may herniate
Meningomyelocele
Meninges and spinal cord herniate during spina bifida
Spina bifida occulta
no herniation during spina bifida
Manx cats
most common breed and species to have spina bifida
Dermoid sinus
incomplete separation of skin and neural tube- residual island of ectoderm in dermis or SQ on midline
Rhodesian ridgeback dogs
most common breed/species to have dermoid sinus
Hydrocephalus
Increase accumulations of CSF within the ventricular system
Hydromyelia
Spinal cord equivalent to hydrocephalus
Syringomyelia
cavitation of spinal cord parenchyma
chiari-like malformation
disease process which will often cause formation of syringomyelia
cavalier king charles spaniel
common breed with chiari-like malformation (syringomyelia)
BVD and Bluetongue virus
2 viruses which will cause hydranencephaly
BVD and feline parvovirus
2 viral causes of cerebellar hypoplasia
feline panleukopenia
the other name for feline parvovirus
hyperammonemia
elevated blood ammonia levels
Hypomyelinogenesis
Underdevelopment of myelin
Dysmyelination
Formation of abnormal myelin
Demyelination
Degeneration and loss of mature myelin
Primary Demyelination
Myelin is destroyed but axon remains
Secondary Demyelination
Degeneration of myelin is secondary to neuronal-axonal injury
Axonopathy
degeneration of axons
Abiotrophy
Premature neuronal death
usually used when talking about cerebellum
Vasogenic edema
Breakdown of blood brain barrier
Cytotoxic edema
Fluid accumulates within astrocytes and their process
malacia
soft and caviated tissue in the nervous system
Fibrocartilaginous embolic myelopathy
Spinal cord infarction secondary to vascular obstruction
Perinatal asphyxia syndrome
Neurologic syndrome of neonatal foals