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Bumetanide
Bumex
(Sulfa Allergy)
1mg PO Bumex = 40mg PO Lasix
1mg IV Bumex = 20mg IV Lasix
Furosimide
Lasix
Protect IV from light
Metolazone
Zaroxolyn
Can be used in renal failure CrCl <30 good to give!
Spironolactone
Aldactone
S/E: Gynecomastia, Impotence (no erection), renal impairment
Maxzide
Hydrocholorthiazide + Traimterene (Dyazide)
Benazepril
Lotensin
Enalapril
Vasotec
Lisinopril
Zestril ; Prinvil
Lisinopril + HCTZ
Zestoretic
Quinapril
Accupril
Ramipril
Altace
(Only ACEI in CAPSULE)
Labetalol
Normodyne
Safe in Pregnancy
Take with food
Nebivolol
Bystolic
Increase Nitric Oxide = Vasodilation
Atenolol
Tenormin
Carvedilol
Coreg , Coreg CR
Take with food
Propranolol
Inderal
Take with Food
Metoprolol Tartrate
Lopressor
IR, take with Food
Metoprolol Succinate
Toprol XL
Can be split.
HF= Start 12.5, increase to target of 200mg/day
Bisoprolol
Zebeta
ZIAC
Bisoprolol + HCTZ
Irbesartan
Avapro
Losartan
Cozaar
Losartan + HCTZ
Hyzaar
Valsartan
Diovan
Valsartan + HCTZ
Diovan HCT
Olmesartan
Benicar
Telmisartan
Micardis
Verapamil
Calan SR, Veralan, Veralan PM
IV, PO
Diltiazem
Cardizem, Tiazac, Tatiana XT
Amlodipine
Norvasc
Felodipine
Plendil
ER, do NOT crush or chew
Nifedipine
Procardia, Procardia XL
Clonidine
Catapres, Catapres TTS,
Kapvay (indicated ADHD)
alpha 2 agonist
1 patch = Q7days
Guanfacine
Tenex = HTN
Intuniv = ADHD
alpha 2 agonist
Hydralazine
Apresoline
Safe in pregnancy
Vasodilator
Prazosin
Minipress
HTN only
Alpha 1 blocker
Doxazosin
Cardura, Cardura XL
Alpha 1 blocker
HTN and BPH
Terazosin
Hytrin (discontinued)
Alpha 1 blocker
HTN and BPH
Tamsulosin
Flomax (Sulfa)
Alpha 1 blocker
Take 300 in after same meal each day
Silodosin
Rapaflo
Alpha 1 blocker
QD with food, can open cap and sprinkle on applesauce
Alfuzosin
Uroxatral
Alpha 1 blocker
Take with same meal each day
Dutasteride
Avodart
5 alpha reductase inh.
BPH, alone or with Tamsulosin
Finasteride
Proscar: 5mg BPH
Propecia: 1mg male baldness
5 alpha reductase inh.
Lotrel
Amlodipine + Benazepril
Tarka
Verapamil + Trandolapril
Prestalia
Amlodipine + Perindopril
Exforge
Amlodipine + Valsartan
Twynsta
Amlodipine + Telmisartan
Azor
Amlodipine + Olmesartan
Caduet
Amlodipine + Atorvastatin
Consensi
Amlodipine + Celecoxib
Isosorbide Dinitrate
Isordil
BID Dose: 8am, 1pm
TID Dose: 8am, 1pm, 6pm
Isosorbide Mononitrate
IR 20mg BID 7 hours apart!!!! (8am , 3PM
Ranolazine
Ranexa
Chronic stable angina
C/I Hepatic impairment
Nitroglycerin
Nitrostat, NitroBID
IV= GLASS!!
Heparin
aPTT:
Normal Dose: LD= 80u/kg ; then 18u/kg/hr
<35 sec: LD 80u/kg —- ↑ 4u/kg/hr
35-45 sec: LD 40u/kg—— ↑ 2u/kg/hr
46-70 sec = at GOAL!
71-90 sec = ↓ 2u/kg/hr
>90 sec = Hold ONE hour, then ↓ 3u/kg/hr
Enoxaparin
Lovenox
Dabigatran
Pradaxa
Direct thrombin inh. (Factor IIa)
Antidote: Idarucizumab (Praxbind)
Keep in original bottle - Open = 4 months
Apixaban
Eliquis
Dose BID
Antidote: Andexnet Alfa (Andexxa)
Rivaroxaban
Xarelto
Antidote: Andexanet Alfa (Andexxa)
Warfarin
Coumadin ; Jantoven
Clopidogrel
Plavix
LD: 300mg then 75mg PO QD
Prasugrel
Effient
Ticagrelor
Brilinta
Warning: Aspirin >100mg reduces its effectiveness
Aggrenox
Dipyridamole + Aspirin
C/I with Salicylate allergy
Amiodarone
Pacerone ; Nexterone
Anti-arrythmic
D/I with Warfarin: ↑ INR
C/I with Sofosbuvir
Dronedarone
Multaq
Anti-arrythmic
WITH FOOD
C/I grapefruit juice
Watch for Liver failure and HF
Sotalol
Betapace ; Betapace AF
Anti-arrythmic
Dofetilide
Tikosyn
Anti-arrythmic
Digoxin
Lanoxin ; Digitek ; Digox
CHF, AFIB
Atorvastatin
Lipitor
Max 80mg
Rosuvastatin
Crestor
Max 40mg, Asian: Max 20mg (start w/ 5mg)
Simvastatin
Zocor
Max 40mg
Pravastatin
Pravachol
Max 80mg
Least Drug interactions
Lovastatin
Mevacor
IR with evening meal
Max 80mg
Gemfibrozil
Lopid
Fibrate
C/I with Statin = myopathy
Fenofibrate
Tricor, Lipofen, Antara, Lofibra
Fibrate
Fenofibric Acid
Trilipix ; Fibricor
Fibrate
Alirocumab
Praluent
PCSK9 Inh
SQ Q2weeks ; fridge
Evolocumab
Repatha
PCSK9 Inh
SQ 140mg Q2weeks or 420mg monthly
Ezetimibe
Zetia
10mg QD
Vytorin
Ezetimibe + Simvastatin
Niacin
Vitamin B3 ; Niacor ; Niaspan
With food
ASA 325mg 30 min before to reduce flushing
Omega 3
Lovaza
increase risk of bleeding with Warfarin
Levothyroxine
Synthroid ; Levoxyl ; Levothyroid
T4
EMPTY STOMACH
Liothyronine
Cytomel ; Triostat
T3
Rapid absorption and onset
Propylthiouracil
PTU
1st trimester of pregnancy!!!!
Methimazole
Tapazole
2nd and 3rd trimester of pregnancy!!!!
Testosterone
Androgel ; Androderm
CIII Med!
Estradiol
Estrace ; Premarin
Oral tab and vaginal cream
Medroxyprogesterone
Provera ; Depo-Provera
oral tabs
Depo= IM/SQ Q3 months
Progesterone
Prometrium
C/I Peanut Allergy!!
CombiPatch
Estradiol + Norethindrone
1 patch weekly - Refrigerated