Cirrus ch 17

Name a medication that is a prodrug

famciclovir

What medication can be used for the treatment or prevention of influenza A and B

oseltamivir

Which class of antiretrovirals is associated with a humped back, facial atrophy, and breast enlargement?

protease inhibitors

what medication is a fusion inhibitor?

enfuvirtide

Which of the following should be avoided when taking delavirdine?

anancids

Which of the viruses below is an example of a latent virus?

herpes

Which of the following non-nucleoside reverse transcriptase inhibitors should be taken with food?

rilpivirine

Name an example of HIV treatments are given subcutaneously?

fusion inhibitors

All the following complementary and alternative therapies have been associated with the reduction of viral infection except

St. Johns' Wort

Name an example of a protease inhibitor?

indinavir

Which of the following antiviral drugs is a powder for inhalation, delivered via a disk inhaler?

zanamivir

Prior to administering an influenza vaccine, it is important to confirm that the patient is not allergic to

eggs

Chemokine coreceptor antagonists are used to treat which of the following conditions?

HIV

The chemical structure of _____ is similar to that of sulfa drugs; therefore, caution must be exercised in patients with a sulfa allergy.

fosamprenavir

With which phase of the HIV life cycle do protease inhibitors interfere?

budding

Give an example of a drug that is associated with the development of diabetes, liver and kidney dysfunction, and kidney stones?

atazanavir

Give an example of a medication can be used to treat diarrhea associated with the use of nelfinavir?

loperamide

Given an example of a HIV drugs can penetrate the central nervous system?

abacavir

Which of the following tasks should a pharmacy technician perform when dispensing Epzicom?

make sure the patient receives a manufacturer's card that will be carried with them at all times

Give an example of a drugs is classified as a nucleoside reverse transcriptase inhibitor (NRTI)?

zidovudine

given an example of a drug that is a fusion inhibitor that prevents HIV from entering immune cells?

enfuvirtide

What is the term used to describe a situation in which preformed antibodies are transferred an individual?

passive immunity

What is a RSV?

reproducing syncytial virus

Give an example of a nucleoside reverse transcriptase inhibitors is available in an injectable dosage form?

zidovudine

What was one of the first drugs created for HIV

zidovudine

What is the first stage of the viral infection within a body?

The virus attaches to cell receptors.

Which of the following vaccines is recommended for healthcare workers?

Hep B

Which of the following vaccines is recommended for patients at high risk of exposure to tuberculosis?

BCG Vacine

Which of the following drugs is approved to treat the block the CCR5 coreceptor and helps prevent HIV from entering?

maraviroc

A(n) _____ viral infection has spread or is spreading to other tissues by way of the bloodstream or tissues of the central nervous system.

generalized

What ingredient found in some oseltamivir formulations should be avoided in neonates?

Benzol Alcohol

Which of the following medications needs to be stored in the refrigerator, but is stable for 60 days when not refrigerated?

tipranavir

In what stage of the HIV life cycle do non-nucleoside reverse transcriptase inhibitors work?

transcription

What is an irreversible skin condition that results from silver accumulation?

argyria

A patient who has a sulfa allergy should not take which of the following protease inhibitors?

darunavir

Which of the following antiviral agents is used to treat genital herpes, herpes zoster, and varicella?

Acylovir

Which of the following terms is used to describe when a fetus receives antibodies during pregnancy from their mother?

passive immunity

Oseltamivir is an antiviral agent used to treat or prevent influenza A or B, but it must be administered within how many hours of symptom onset?

48 hours

Which of the following nucleoside reverse transcriptase inhibitors may cause hyperpigmentation on the palms or soles?

emtricitabine

Which of the following non-nucleoside reverse transcriptase inhibitors has the greatest risk of liver toxicity that may result in liver failure or death during the first five months of therapy?

nevirapine (NNRTI)

Why must extra precautions be taken when administering the FluMist vaccine?

It is a live attenuated virus.

Jaundice is a common side effect of which of the following protease inhibitors?

atazanavir

Nucleoside reverse transcriptase inhibitors and nucleotide reverse transcriptase inhibitors work by which of the following mechanisms?

inhibiting reverse transcriptase

Which of the following vaccines must be refrigerated and taken with lukewarm water about one hour prior to eating?

typhoid vaccine

Which of the following nucleoside reverse transcriptase inhibitors should be taken on an empty stomach?

efavirenz

Herpes simplex types 1 and 2 are associated with which of the following infections?

oral and genital herpes

What is required to be given to patients when they are signing a consent form?

vaccine information statement

What term describes the effect in which a drug increases the serum concentration of another drug?

boost

What advantage does famciclovir have over other antiviral agents?

dosed less frequently

Which of the following is an enzyme that integrates HIV DNA into the DNA of the host CD4 cell?

integrase

The vaccination with the brand name Vaqta is used as a prophylactic for which virus?

Hep A

Which of the following NRTIs is available as an injection?

Retrovir

Which of the following is the only fusion inhibitor available?

(disrupt the HIV envelope from merging with the host CD4 + cell membrane)

enfuvirtide

Which of the following viral infections, under certain conditions and possibly years after the initial breakout or transmission of the infection, may reproduce and again behave like an infective agent?

herpes

A viral infection that is quick to resolve with no latent infection, such as the common cold, is an example of a(n) _____ viral infection.

acute

Which of the following antiviral agents has a boxed warning regarding its mutagenic properties?

valganciclovir

Which of the following non-nucleoside reverse transcriptase inhibitors can cause a false cannabinoid test?

efavirenz

What is the most common cause of lower respiratory tract infections in infants?

RSV (Respiratory Syncytial Virus )

Acyclovir can decrease the therapeutic effect of varicella and _____ vaccines?

zoster

Which of the following non-nucleoside reverse transcriptase inhibitors should be given at bedtime and is known to induce vivid dreams, nightmares, and hallucinations?

efavirenz