Looks like no one added any tags here yet for you.
within the skull and spinal column
Where is the central nervous system (CNS) located?
analyzing incoming information
What is the purpose of the CNS?
outside the skull and spinal column
Where is the peripheral nervous system (PNS) located?
messenger that allows info to travel to/from the CNS
What is the purpose of the PNS?
1. Somatic nervous system
2. Autonomic nervous system
What are the two subdivisions of the PNS?
involved with EXTERNAL sensations, takes info from the outside (sound, smell, etc) and sends to the brain. Also responsible for VOLUNTARY skeletal movements (blinking, grabbing)
What is the purpose of the somatic nervous system?
involved with INTERNAL sensations (stomach hurts). Also responsible for INVOLUNTARY/AUTOMATIC responses (blood vessels changing size, digestion, heart rate)
What is the purpose of the autonomic nervous system?
ACCEPTING signals to the CNS. SENSORY information from muscles/joints/etc
What is the purpose of afferent nerves?
EXITING the CNS. MOTOR signals from CNS to muscles
What is the purpose of efferent nerves?
activation of system (prepare for action)
ex: Dilates pupils, accelerates heartbeat, inhibits digestion
What is the purpose of the sympathetic division of the autonomic nervous system?
action of system (relax, recuperate)
ex: Constricts pupils, constricts airways, slows heartbeat, stimulates digestion
What is the purpose of the parasympathetic division of the autonomic nervous system?
Soma
cell body. contains majority of organelles; organelles involved in various functions
Nucleus
within the cell body. contains DNA which is used to influence neuronal function
Dendrites
branch-like extensions from cell body which have receptors that become stimulated from outside signals (receives messages)
Axon hillock
cone-shaped location which connects the cell body to the axon. This is where electrical signals sum together and where the action potential starts
Axon
cord-like extension from soma via axon hillock. conducting electrical impulses away from soma (sends messages)
Myelin sheath
fatty bilayer which covers axons and helps speed up neuronal transmissions
Nodes of ranvier
unmyelinated segment on the axon measuring about 1 micrometer in length. Involved in saltatory conduction/speeding up neuronal transmission
What is the axon terminal?
ends of axon which branch out into knobs, forming a synapse on another neuron or other cell target (often referred to as presynaptic terminal when signaling)
Multipolar neuron
MULTIple dendrites, 1 axon (typical image of neuron)
Bipolar neuron
1 dendrite, 1 axon (2 lines with bulbous looking soma in middle)
Pseudounipolar neuron
0 dendrites, 2 branching axons. Sends AND receives signals. (very weird one)
Sensory category of neuronal function
carries info from periphery to CNS. Pseudounipolar. AFFERANT. “A” for Accepted by the CNS
Motor category of neuronal function
carries info from CNS to muscles. Multipolar. EFFERANT. “E” for Exiting the CNS
Interneuron category of neuronal function
contained in CNS, don’t extend far. Communicates between sensory and motor neurons inside the CNS. Multipolar. Quick, automatic responses, like reflexes (stepping on lego)
Astrocyte (glial cell)
star-shaped, form the blood-brain barrier and clean up waste
Microglia (glial cell)
smallest, act as the CNS’ immune system. Target disease, break down damaged cells.
Promote growth
Oligodendrocyte (glial cell)
found in CNS, produces nodes of ranvier
Schwann Cell (glial cell)
found in PNS, produces bundles of myelin around axon
Sodium (Na+)
positive charge – Wants to move into the cell
Potassium (K+)
positive charge - Wants to move into the cell
Chloride (Cl-)
negative charge - Wants to move out of the cell
threshold for action potential
-55 mV
The sodium-potassium pump works to restore ion balance by trading 3 Na+ out for every 2 K+ ions in
How is ion balance restored?
resting potential of a neuron
-70 mV
Depolarization
when the cell becomes more positive
Hyperpolarization
when the cell becomes more negative
Absolute refractory period
At the peak, the axon cannot generate another AP because Na+ channels are closed and are in a short inactive state where they CANNOT reopen
Relative refractory period
On the downward turn, another AP can be generated, but a stronger stimulus is needed.
Presynaptic cell
The cell that is delivering a signal
Postsynaptic cell
The cell that is receiving a signal
Temporal summation
Repeated stimuli have a cumulative effect
- Continuously activating the same neuron within a short time frame (squeezing dog paw at random times in same spot)
Spatial summation
Stimuli at separate, but close locations have a cumulative effect and trigger a nerve impulse
- Sending multiple synaptic inputs to a neuron at the same time (squeezing dog paw in random spots but similar area)
Excitatory postsynaptic potential (EPSP)
temporary depolarization of a membrane
Inhibitory postsynaptic potential (IPSP)
temporary hyperpolarization of a membrane
Glutamate
major excitatory NT. EPSP (opens sodium channels)
GABA
major inhibitory NT. IPSP (opens potassium or chloride channels)
Acetylcholine
NT with role in movement/muscle contraction
Dopamine
NT important for initiation/smoothness of movement, reward, pleasure, decision-making
Serotonin
NT important for stable mood. Major target for antidepressant drugs
Transporter receptors
special membrane proteins that facilitate reuptake (PRESYNAPTIC)
Autoreceptors
receptors that detect the amount of transmitter released and inhibit further synthesis & release (PRESYNAPTIC)
Ionotropic receptors
receptor that uses ligand gated channel, occurs quickly (POSTSYNAPTIC)
Metabotropic receptors
receptor that uses signal proteins, slower (POSTSYNAPTIC)
Neurotransmitters
chemicals that travel across the synapse and allow communication between neurons
Neuropeptides
EPSPs who’s release requires repeated stimulation. Effects are long lasting. Important for long-lasting behaviors like hunger and thirst
Hormones
chemicals secreted by a gland (or other cells) to be transported to other organs by the blood, and then alters activity there. Made by chains of amino acids
Dorsal
toward the back; toward the top of the head (forehead up)
Ventral
toward the chest; toward the bottom of the head (forehead down)
Anterior
towards the front/nose
Posterior
towards the back/butt
Superior
towards the top of the brain; above another structure
Inferior
towards the bottom of the brain; below another structure
Medial
towards the midline of the body (spine/middle of brain)
Lateral
away from the midline of the body (moving to the sides)
Proximal
located closely to the point of attachment or origin
Distal
located more distant to the point of attachment or origin
Lamina
a row of cell bodies separated from other cell bodies by a layer of axons and dendrites
Column
a set of cells perpendicular to the surface of the cortex
Tract
a bundle of axons within the CNS
Nerve
a bundle of axons running from the PNS to the outskirts of the CNS
Nucleus
a cluster of neuron cell bodies within the CNS that are specialized in a certain function
Ganglion
a cluster of neuron cell bodies in the PNS that are specialized in a certain function
Gyri/Gyrus
a protuberance on the surface of the brain (thick fleshy bumps)
Sulci/Sulcus
a fold or groove that separates one gyri from another (the wrinkles)
Fissure
a long deep sulcus (grand canyon for brain)
Cerebral cortex
large outer portion of brain with 4 lobes
Divided into 2 hemispheres. Connected by 2 bundles of axons: Corpus callosum, Anterior commissure
Occipital lobe
important for vision. Contains the primary visual cortex. Damage can result in cortical blindness. (person is able to see but can’t process that they are seeing)
Parietal lobe
primary somatosensory cortex. important for somatic sensations (touch) and spatial awareness
Temporal lobe
primary auditory cortex. Essential for processing spoken language
Frontal lobe
prefrontal cortex, important for higher order functioning (planning, decision making, personality, etc.). Primary motor cortex, responsible for the control of fine motor movement
Thalamus
relay station from the sensory organs; main source of input to the cortex
Hypothalamus
Conveys messages to the pituitary gland to alter the release of hormones. “Four F’s” – fight, flight, feeding, fornication
Diencephalon
thalamus + hypothalamus
Pituitary gland
hormone-producing gland
Basal ganglia
Associated with the planning of motor movement. Critical for learned skills and habits.
Hippocampus
Critical for storing certain types of memory (new events). Episodic, Spatial navigation, Temporal. Seahorse shape
What is contained in the forebrain?
Cerebral cortex, thalamus, hypothalamus, pituitary gland, basal ganglia, hippocampus
What is contained in the midbrain?
Tectum, tegmentum, superior colliculus, inferior colliculus, substantia nigra
Tectum
“roof”/dorsal part of the midbrain
Superior colliculus
processes visual info and eye muscle movement
Inferior colliculus
processes auditory information
Tegmentum
”floor”/ventral part of the midbrain
Substantia nigra
gives rise to the dopamine-containing pathway facilitating readiness for movement
What is contained in the hindbrain?
Medulla, pons, cerebellum
Medulla
Responsible for vital functions needed for survival – breathing, heart rate, vomiting, salivation, coughing & sneezing. YOU WILL DIE IF IT IS DAMAGED!!!!!
Pons
relays sensory and motor info between the cerebellum and cerebrum
Cerebellum
helps regulate motor movement, balance, coordination
Ventricles
4 brain cavities filled with cerebrospinal fluid
Cerebrospinal fluid
Fluid found in brain and spinal cord. Cushions brain, reservoir for hormones and nutrition, removes chemical wastes