Gas exchange (WORK)

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15 Terms

1
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What is gas exchange

Exchange of CO2 and O2 at cells and tissues through diffusion

2
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List 5 adaptations of gas exchange surfaces

  • Large surface area

  • Thin tissue layer (1 cell thick)

  • Permeable membranes

    Dense network of capillaries with constant blood flow surrounding to maintain concentration gradient for diffusing gases

  • Covered in layer of moisture: allows gas to dissolve and diffuse rapidly

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Respiration

Release of ATP energy from organic compounds in cells.

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What is partial pressure? What factors affect it

Pressure exerted by single gas when its found in mixture of gasses

  • Total pressure exerted by all gas in the mixture

  • Concentration of target gas

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Low partial pressure of O2

Low haemoglobin affinity to O2

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High partial pressure of O2

High haemoglobin affinity to O2

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O2 dissociation curve (x and y axis, Shape description)

Shows affinity of haemoglobin for oxygen

  • X axis = partial pressure

  • Y axis = O2 saturation of haemoglobin

Sigmoid shape

  • Start at low PP low saturation.

  • PP increase, saturation increase

  • High PP, curve flattens out because most haemoglobin are fully saturated

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What is the max amount of O2 that can bind with 1 Haemoglobin

4

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What happens to affinity for O2 when more O2 binds to 1 haemaglobin

Conformational change in shape of haemoglobin occurs

Increases affinity o

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What is co-operative binding

When binding of one molecule to another facilitates the binding of another to the same molecule

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O2 Partial pressure in the lungs

HIgh partial pressure. Haemoglobin becomes fully saturated

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O2 Partial pressure in respiring tissue

Respiring tissue uses O2, low concentration of O2, and low Partial pressure of O2

Haemoglobin release O2, diffuse into respiring tissue to provide more O2.

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CO2 modes of transport (3)

  1. Some CO2 is bounded in haemaglobin

  2. Small amount of CO2 dissolved in blood plasma

  3. Most CO2 is reversibly converted to HCO2 + ion in blood cells

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Difference between Foetal and Adult Haemoglobin

Foetal: 2 alpha 2 gamma haemoglobin parts

Adult: 2 alpha 2 beta