2.1 Origin of Cells

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Alexander Oparin and JBS Haldane steps for how life originated

  1. Formation of simple organic molecules from inorganic compounds

  2. Assembly of carbon compounds into polymers

  3. Formation of a polymer that can self-replicate

  4. Packaging of molecules into compartments with an internal chemistry different from its surroundings 

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Early Earth’s atmosphere

  • water vapour

  • high levels of co2

  • methane

  • amonia

  • hydrogen sulfide

  • hydrogen

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Miller and Harold Urey 

Recreated early earth’s atmosphere in a closed system:

  • low oxygen levels

  • high radiation

  • high temperatures

  • sparks (lightning storms)

  • water vapour, ammonia, methane hydrogen

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Result of Miller and Harold Urey experiment

  • Long hydrocarbon chains

  • 15 of 20 amino acids

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Issues with Miller and Harold Urey’s experiment

  • no definitive evidence of compounds on earth’s atmosphere

  • some theorised hydrocarbons were brought to Earth by meterorites

  • Methane and ammonia would not be present

  • absence of gases creates a non-reducing environment meaning carbon atoms can’t be formed

  • proteins break down in water based environment