Pheochromocytoma or Neuroblastoma

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8 Terms

1
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Only drug for pheochromocytoma or Neuroblastoma

Adreview (I-123 MIBG)

2
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Adreview (I-123 MIBG) physical characteristics

MIBG is an analog of norepinephrine

High expression in norepinephrine transporter (NET)

3
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Adreview (I-123 MIBG) Indication

Detection of primary or metastatic pheochromocytoma or neuroblastoma

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Adreview (I-123 MIBG) biological processing

Tumors have high expression of NET. MIBG is an analog of norepinephrine, transported into the cell and stored in the mitochondria

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Adreview (I-123 MIBG) application

High degree of sensitivity for locoalization of NETs

After diagnosis Azedra (I-131 MIBG) can be used for treatment

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Adreview (I-123 MIBG) dosage

2-10 mCi

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Adreview (I-123 MIBG) MOA

active transport of MIBG through NET transporters as analog of norepinephrine

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Adreview generic name

I-123 MIBG