Thymus Stucture and T Cell Maturation
0.0(0)
Studied by 0 people0.0(0)
Call with Kai
Learn
Practice Test
Spaced Repetition
Match
Flashcards
Knowt PlayCard Sorting
1/9
There's no tags or description
Looks like no tags are added yet.
Study Analytics
Name | Mastery | Learn | Test | Matching | Spaced | Call with Kai |
|---|
No study sessions yet.
10 Terms
1
New cards
Where is the thymus located?
Anterior mediastinum
2
New cards
What are the two main regions of each thymic lobule?
Cortex and medulla
3
New cards
Which cells populate the thymus besides lymphocytes?
Epithelial cells, macrophages, dendritic cells
4
New cards
Where do pro-lymphocytes enter the thymus?
Cortex via blood vessels
5
New cards
Where does positive selection occur?
Cortex
6
New cards
Where does negative selection occur?
Medulla
7
New cards
What phenotype do thermocytes express before selection?
CD4+ CD8+ (double positive)
8
New cards
What do mature T cells become after selection?
Single positive (CD4+ or CD8+)
9
New cards
What happens to T cells that fail to recognise self-MHC?
Die by neglect
10
New cards
What happens to T cells with high affinity for self-antigen?
Clonal deletion
Note 
Flashcards (58)