PPC DRUGS 41-50

generic: acetaminophen

brand: tylenol

acetaminophen drug class

drug class: non-opioid analgesic

acetaminophen indications

indications: minor pain, antipyretic (fever reduction)

generic: ibuprofen

brand: advil, motrin

ibuprofen drug class

drug class: NSAID, non-opioid analgesic;

Hint: brand name is motrin/advil

ibuprofen indications

indications: fever, mild to moderate pain, osteoarthritis, inflammatory diseases, rheumatoid diseases

generic: naproxen

brand: aleve

naproxen drug class

drug class: NSAID, non-opioid analgesic;

Hint: brand is Aleve/Naprosyn

naproxen indicatiosn

indications: fever, mild to moderate pain, osteoarthritis, inflammatory diseases, rheumatoid diseases

generic: celecoxib

brand: celebrex

celecoxib drug class

drug class: COX-2 selective NSAID, non-opioid analgesic

celecoxib indications

indications: acute pain, osteoarthritis, rheumatoid arthritis, juvenile idiopathic arthritis (JIA), acute migraine; prescription

generic: fentanyl transdermal

brand: duragesic

generic: hydrocodone/acetaminophen

brand: lortab, norco, vicodin

generic: oxycodone ER

brand: oxycontin

generic: oxycodone IR

brand: oxy IR, roxicodone

generic: oxycodone/acetaminophen

brand: percocet

generic: tramadol

brand: ultram

Acetaminophen Adverse

-Skin rash (rare but serious)

-Liver Damage

Celecoxib and NSAID Adverse

-CV and GI risk

-Kidney Disease

NSAID COX 1/2 Adverse

-Anticoagulant / anti-platelet avoid —> bleed risk

-Take w/ food 

Opioids Boxed Warnings

-Addiction, misuse, abuse

-Risk evaluation and mitigations strategy

-Life-threatening resp. depression

-Accidental ingest / med errors

-Risk w/ benzodiazepines & CNS depressants

-CYP3A4 drug interactions

Opioids Adverse

-Nausea / vomiting

-Drowsy / dizzy

-Constipation

Opioids Counseling

-Bowel regimen

-Take w/ food

-Educate on serious effect

Which drug has less GI risk?

Just cox-2 inhibitor (celecoxib)

Most opiods are CII where you cannot refill, except ________, which you can refill 5 times in 6 months

Tramadol (ultram)

Opioid Indication

-acute / chronic pain (ER)

-when no other pain reliever works

-Postoperative

-Cancer