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Striated Muscle Cells
Multi-nucleated cells, challenges cell theory
Red Blood Cells
No nuclei and does not replicate, challenges cell theory
Fungal Hyphae
Cells that appear to be roots, multi nucleated, challenges cell theory
Phloem Sieve Tube
Have no organelles, yet are still considered cells, challenges cell theory
Myxococcus xanthus
Rod-shaped bacterium, differentiates into spores
Slime Mould
A colony of single celled organisms that can form a multi cellular body
Retinoic Acids
Guides differentiation of forelimbs, pancreas, lungs, kidneys
Bone marrow
Multipotent blood cell
erythrocytes
flat disc shape cells, increases S.A
Proximal convoluted tubles
In kidney, has microvilli that increase S.A
Potassium and glucose
Hydrophillic glucose bonds to potassium which can pass bilayer, example of active transportation and passive transportation
Budding Yeast Cells
unequal cytokinesis (budding), small cell receives nucleus and buds off
Oogenesis
unequal cytokinesis of oocyte (egg), only egg stays, sperm absorbed
Bacteriophage
DNA virus, both positive and negative strand DNA, non-enveloped, targets gram - bacteria like e-coli
COVID-19
RNA virus, positive sense, enveloped, zoonotic from bats, targets mammalian cells
HIV
RNA retrovirus, reverse transcription, enveloped, targets t-cells
Cholesterol
Lipid, steroid, precursor template steroid
Adipose Tissues
Layer of connective tissue between skin and organs
Lipoproteins
carries hydrophobic substances in blood
LDL
Low-density lipoprotein, bad cholesterol, builds up into plaque
HDL
High-density lipoprotein, good cholesterol
Hemoglobin
Conjugated protein, iron as prosthetic group
Insulin
Non-conjugated protein
Enzymes
Globular proteins, circular for S.A
Phosphodiester Bonds
Bonds formed between DNA replication
Glycosidic Bond
Bonds formed between carbohydrates
Peptide Bond
Bonds formed between amino acids
DNA Replication
Semi-conservative, keeps half new half old
Which enzyme proof reads the new DNA?
DNA Polymerase III
Okazaki Fragments
Fragments on lagging strands, lack of phosphodiester bonds
TAQ DNA Polymerase
Originated from Thermus aquaticus, a prokaryote, has high heat tolerance
Examples of non-coding DNA
STR, enhancers, silencers, telomeres
what theory proposes that information flows only in one direction?
Theory of Molecular Biology
Post Transcription modifications
Poly-A Tail, splicing, methyl cap
Proteasomes
Large protein that breaks unused protein to be recycled
Transcriptional gene regulation
Methylation - reduces transcription via methyl groups, environmental
Nucleosome spacing - more space between nucleosomes allow control of transcription
Sickle Cell Disease
Base substitution change (nitrogenous base), has its own allele (normal is hemoglobin)
Difference between homologous and sister chromosomes?
Homologous have same genes, different alleles; sister chromatids have same gene and allele
Can prokaryotic cells share genetic material?
Yes, via conjugation
Methods of karyotyping
Amniocentesis, chorionic villi sampling
Germinal cells
Cells that only go through meiosis (egg, sperm)
The resulting genes after crossing over are?
Recombinant chromosomes
Place where bivalent chromosomes cross over?
Chiasma
Example of incomplete dominance?
Four o clock marvel flower
Example of codominance?
Blood typing
Example of autosomal recessive disease?
Phenylketonuria (PKU), cause phenylalanine to build up due to a lack of enzyme production
Example of a sex-linked disease
Hemophilia, blood fails to clot properly
Phenotypic plasticity vs adaptation?
Phenotypic plasticity changes the phenotype expression but retains genotype. Adaptation changes the gene pool
Main components of CRISPR
CAS9 enzyme (viral origins) splits desired DNA and gRNA delivers enzymes. PAM sequences are where spacers share a common sequence that’s targeted by cas.
Examples of mixotrophs
Dodder, euglena
Example of mutalism
Rhizobia (bacteria) and fabacea (legume)
Example of invasive species
Red lionfish
Example of a biomagnification toxin?
DDT, results in weakened egg structure after accumulating in birds
Examples of pioneer species
Moss, grass, lichen
Factors of Biodiversity Crisis
Agriculture, overexploitation, urbanization, deforeatstion, pollution, invasive species/disease
Difference between Eukaryotes and Prokaryotes
Eukaryotes:
1. 80s ribosomes
2. Membrane bound organelles
3. DNA in nucleus
Prokaryotes:
1. 70s ribosomes
2. Non-bounded membrane organelles
3. DNA in nucleoid
Oligosaccharides
sugar chains on glycoproteins and glycolipids
Which experiment disproved spontaneous generation?
Louis Pasteur’s swan-neck flask experiment
Which experiment supported the theory of abiogenesis?
Miller-Urey experiment producing simple carbon compounds
Evidence for mitochondria and chloroplasts being bacterias
1.Circular DNA
2. Similar membrane structure
3. 70s ribosomes
4. can self-replicate
Positive sense vs negative sense viruses
positive sense uses gene to make mRNA; negative sense transcribes genes in order to make mRNA
Progressive hypothesis
virus came before cells due to their simplicity; virus like components in some cells
Regressive hypothesis
Viruses came after cells due to loss of cell components; virus need hosts
Why does HIV rapidly evolve?
reverse transcriptase doesn’t check for errors
methylation
methyl groups are added to DNA which reduces rate of transcription
nucleosome spacing
more space between nucleosomes leading to more transcription
gene, locus, allele
gene - section of DNA; locus - position of gene; allele - different ver of gene
statins
competitve inhibitor that lowers LDL
Penicillin
permanent competitive enzyme inhibitor; targets transpeptidase
What is an example of an end-product inhibition?
threonine being converted to isoleucine