Pcog: Alkaloids w/ Structures

Cocaine

Contains two ester functions

Quinine

Contains both secondary alcohol and aromatic methoxy functions. Antimalarial in many parts of the world. Diastereo-isomer of quinidine

Ergonovine

Contains two subsided amide function; Principal component of the water-soluble fraction

Atropine

True alkaloids thar are derived from amino acids and have nitrogen in a heterocyclic ring. Antidote in poisoning caused by cholinesterase inhibitors

Ephedrine

Protoalkaloids that are derived from amino acids and do not have nitrogen in a heterocyclic ring

Caffeine

Pseudoalkaloids that are not derived from amino acids but have nitrogen in a heterocyclic ring; 1,3,7-trimethyl-xanthine; CNS Stimulants

Arecoline

Employed as vermicide and taeniafuge

Lobeline

Smoking deterrent

Nicotine

Product of root metabolism

Hyoscyamine

Parasympatholytic

Scopolamine

Anticholinergic

Cinchonine

Antimalarial

Quinidine

Principal alkaloid employed therapeutically

Emetine

Emetic; For treatment of drug overdose and certain poisoning

Hydrastine

Astringent in the inflammation of the mucous membrane

Tubocurarine

Skeletal muscle relaxant; Diagnostic aid in myasthenia gravis

Morphine

Most important opium alkaloid; centrally acting analgesic

Codeine

Methyl morphine; Most widely used opium alkaloid; Narcotic analgesic and antitussives

Heroin

Diacetylmorphine; Formed by acetylation of morphine

Reserpine

Hypotensive

Strychnine

Extremely toxic (valuable tool in physiologic and neuroanatomic research

Vinblastine & Vincristine

Folkloric use as oral hypoglycemic; The most characteristic effect of these drugs is the arrest of cell division at the metaphase

Pilocarpine

Cholinergic (ophthalmic) drugs used in the treatment of glaucoma

Protoveratrine

Hypotensive

Theophylline

1,3-dimethylxanthine; Isomeric with theobromine; Used principally as smooth muscle relaxant

Theobromine

3,7,-dimethylxanthine; Diuretic and smooth muscle relaxant