ALKALOIDS: Precursor and Definition

• Pyridine-Piperidine

• Tropane

• Quinoline

• Isoquinoline

• Indole

• Imidazole

• Steroidal

• Alkaloidal Amines

• Purines

Enumerate the alkaloids

Ornithine

Precursor of Tropane

Tryptophan

Precursor of Quinoline

Tyrosine

Precursor of Isoquinoline

Tryptophan

Precursor of of Indole

Histidine

Precursor of Imidazole

• Tyrosine

• Phenylalanine

• Tryptophan

Precursor of Alkaloidal Amines

Ornithine

Precursor of Pyridine-Piperidine

Quinoline

Alkaloids that contain ___ as their basic nucleus; obtained from the Cinchona plant.

Steroidal

Has a Mentions a cyclopentano phenanthrene nucleus.

Alkaloidal Amines

Known as protoalkaloids, these do not contain heterocyclic nitrogen atoms. They are derivatives of phenylethylamine or tryptamine.

Purines

Derivatives of a heterocyclic nucleus consisting of a 6-membered pyrimidine ring fused to a 5-membered imidazole ring.

• quinoline

• Cinchona

Quinoline is alkaloid that contains ___ as their basic nucleus; obtained from the ___ plant.

Protoalkaloids

Alkaloidal Amine are also known as?

• 6-membered pyrimidine ring fused to a 5-membered imidazole ring

Purines are derivatives of a heterocyclic nucleus consisting of a ___

• Cinchonine (main)

• Cinchonidine

Parent alkaloids of Quinoline

• Quinine

• Quinidine

Parent alkaloids of Quinoline forms what?

• Phenylethylamine

• Tryptamine

Alkaloidal amines are derivatives of?

• Tyrosine or Phenylalanine

Constituent of Alkaloidal amines that are derivatives of phenylethylamine

Tryptophan

Constituent of Alkaloidal Amines that are derivatives of tryptamine

Phosphodiesterase enzyme

Purine alkaloids inhibit what enzyme for relaxation of smooth muscles, bronchi, etc., stimulate the CNS

• Gastric acid

• Heart contractility

• Diuretic effect

Purines increase what?

• cAMP

• AMP

Phosphodiesterase is an enzyme responsible for converting ___ to ___