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Curt Richter
proposed that the body generates its own cycles of activity and inactivity
endogenous circannual rhythm
an internal calendar that prepares a species for annual seasonal changes
circadian rhythm
A physiological cycle of about 24 hours that is present in all eukaryotic organisms and that persists even in the absence of external cues.
Zeitgeber
stimulus that resets the circadian rhythm
Human circadian clock generates a rhythm slightly_________ 24 hours when it has no external cue to set it
longer than
Suprachiasmatic Nucleus (SCN)
the body's way of monitoring the change from day to night.
-Main control center of the circadian rhythms of sleep and temperature
Damage to the SCN
Results in less consistent body rhythms that are no longer synchronized to environmental patterns of light and dark
retinohypothalamic pathway
the route by which retinal ganglion cells send their axons to the suprachiasmatic nuclei.
-Cells respond directly to light and do not require any input from the rods or cones
- Light resets the SCN
Two types of genes responsible for circadian rhythm
PER: Period
TIM: Timelessness
Mutation in Period Gene
PER gene result in odd circadian rhythms or decreased alertness if deprived of a good night's sleep
Melatonin
A hormone manufactured by the pineal gland that produces sleepiness.
Stage 1 sleep
- decline in brain activity;
- Alpha waves are present ;
- EEG show Irregular, jagged, and low voltage waves
Stage 2 sleep
A sleep deeper than that of stage 1, characterized by a slower, more regular wave pattern, along with momentary interruptions of "sleep spindles."
K-complex: a sharp wave associated with temporary inhibition of neuronal firing
Slow wave sleep (Stages 3 and 4)
EEGs reveal large, regular delta waves and sleepers are hard to awaken.
-Slowing of heart rate, breathing rate, and brain activity
paradoxical sleep (REM)
deep sleep in some ways, but light sleep in other ways
Rapid eye movements during sleep
When people fall asleep, they progress through stages 1, 2, 3, and 4 in _______________________.
sequential order.
Reticular formation
part of the midbrain that extends from the medulla to the forebrain and is responsible for arousal
Pontomesencephalon
contributes to cortical arousal
-Stimulation of the pontomesencephalon awakens sleeping individuals and increases alertness in those already awake
Locus coeruleus
is involved in directing attention
Orexin (hormone)
hunger-triggering hormone secreted by hypothalamus
Sleep and the Inhibition of Brain Activity
Functions of the inhibitory neurotransmitter GABA are also important for:
- Decreasing the temperature and metabolic rate
- Decreasing the stimulation of neurons
Sleep can be localized within the brain
sleepwalkers and lucid dreamers
REM is interrupted by ______________, and __________ causes you to reach REM faster
Serotonin; Acetylcholine
PGO waves are associated with
REM sleep
During REM sleep activity is _____________ in the pons and limbic system.
Increased
During REM sleep activity is __________ in the primary visual cortex, the motor cortex, and the dorsolateral prefrontal cortex.
Decreased
Sleep Apnea
inability to breathe while sleeping for a prolonged period of time
Narcolepsy
A sleep disorder characterized by uncontrollable sleep attacks. The sufferer may lapse directly into REM sleep, often at inopportune times.
Periodic Limb Movement Disorder
repeated involuntary movement of the legs and sometimes arms during sleep
REM Behavior Disorder
a sleep disorder in which a person does not lose muscle tone during REM sleep, allowing the person to act out dreams
Night Terrors
Experiences of intense anxiety from which a person awakens screaming in terror
Sleepwalking
walking or carrying out behaviors while asleep
Functions of Sleep
memory consolidation, energy conservation, helps restore bodily functions
Hibernation
Long-term torpor that is an adaptation to winter cold and food scarcity.
Parkinson's Disease
Characterized by muscle tremors, rigidity, slow movements, and difficulty initiating physical and mental activity
Immediate Cause of Parkinson's
Caused by gradual and progressive death of neurons, especially in the substantia nigra
Loss of dopamine leads to less stimulation of the motor cortex and slower onset of movements
Treatment of Parkinson's Disease
The drug L-dopa is the primary treatment for Parkinson's and is a precursor to dopamine that easily crosses the blood-brain barrier
Drugs that directly stimulate dopamine receptors
Implanting electrodes to stimulate areas deep in the brain
Huntington's Disease
Associated with gradual and extensive brain damage especially in the basal ganglia but also in the cerebral cortex
Initial motor symptoms include arm jerks and facial twitches
Readiness potential
is a particular type of activity in the motor cortex that occurs before any type of voluntary movement
we become conscious of the decision to move ________ the process has begun
After
Basal ganglia select a movement to make by ______ to inhibit it
ceasing
Movement as directed by structures of the basal ganglia
(Caudate nucleus) and (putamen) receive input from the cerebral cortex and send output to the (globus pallidus)
Globus pallidus connects to the thalamus, which sends information to the motor areas and the prefrontal cortex
Release of ___________ causes the muscle to contract
acetylcholine
A neuromuscular junction is a
synapse between a motor neuron axon and a muscle fiber
Muscles are composed of
many individual fibers
Antagonistic Muscles
muscle pairs arranged to work against each other to move a joint
flexor muscle
bends a limb at a joint
extensor muscle
straightens a limb at a joint
__________ always excites skeletal muscles to contract
Acetylcholine
Fast-twitch
fibers produce fast contractions but fatigue rapidly
Slow-twitch
fibers produce less vigorous contraction without fatigue
Proprioceptors
receptors that detect the position or movement of a part of the body
Muscle spindles respond to a _________: cause a ___________ of the muscle
stretch; contraction
Golgi tendon organ responds to ___________ in muscle tension
increase
Primary motor cortex (M1) is located in the __________ which is located in the____________.
precentral gyrus; frontal lobe
Axons from the precentral gyrus connect to the _________ and the ________, which generate impulses that control the muscles
brainstem; spinal cord
Posterior parietal cortex
keeps track of the position of the body relative to the world
Premotor cortex
area of the frontal cortex, active during the planning of a movement
Supplementary motor cortex
area of the frontal cortex; active during preparation of a rapid sequence of movements
Mirror Neurons
neurons in the brain that are activated when one observes another individual engage in an action and when one performs a similar action
Messages from the brain must reach the _______ and ________ to control the muscles
medulla; spinal cord
What are the two types of Corticospinal tracts?
Lateral corticospinal tract
Medial corticospinal tract
Medial corticospinal tract
Vestibular nucleus is a brain area that receives information from the vestibular system
Axons extend from one side of the brain to the both sides of the spinal cord
Lateral corticospinal tract
Branches at the brainstem level, crossing over to the opposite side of the brain and spinal cord
Moves the digits and limbs on the opposite side of the body
Corticospinal tracts are paths from the___________ to the __________.
cerebral cortex; spinal cord
Paralysis
temporary or permanent loss of motor control
Paraplegia
paralysis of both legs and the lower part of the body
Quadriplegia
paralysis of all four limbs
Hemiplegia
paralysis of one side of the body
Tabes dorsalis
Late stage syphilis
Impaired sensation in the legs and pelvic region, impaired leg reflexes and walking, loss of bladder and bowel control.
Poliomyelitis
a viral infection of the gray matter of the spinal cord that damages cell bodies of motor neurons.
Resulting in Paralysis
Amyotrophic lateral sclerosis (ALS)
a rapidly progressive neurological disease that attacks the nerve cells responsible for controlling voluntary muscles
What are sound waves?
pressure changes in the atmosphere capable of being detected by auditory organs
What is the amplitude?
The magnitude and direction of displacement. The greater the amplitude, the louder the sound signal.
What is frequency of a sound?
the number of waves that pass a point in a certain amount of time
Timbre
quality of sound
___________ are better at hearing higher frequencies than ____________.
Children; Adults
Alteration of pitch, tone of voice, volume or timbre can convey
Emotion
outer ear
The part of the ear that collects sound waves; consists of the pinna, the ear canal, and the eardrum.
middle ear
the chamber between the eardrum and cochlea containing 3 tiny bones (hammer, anvil, and stirrup) that concentrate the vibrations of the eardrum on the cochlea's oval window
auditory pathway
outer ear (pinna) - ear drum - middle ear bones - oval window - cochlea - cochlear nucleus - superior olive - inferior colliculus - medial geniculate nucleus - auditory cortex
Inner ear
the innermost part of the ear, containing the cochlea, semicircular canals, and vestibular sacs
Oval Window transmits waves through ______________
viscous fluid
Snail shaped organ in ear
cochlea
3 fluid filled chambers of the cochlea
hint: the scala sisters like to watch videos, trailers, on twitter.
1. scala vestibuli
2. scala tympani
3. scala media
The hair cells are auditory receptors that lie between the _________________ and the __________________ of the cochlea.
Basilar membrane; Tectorial membrane
Movement of hair cells
results in excitation of the auditory nerves
place theory of pitch perception
different portions of the basilar membrane are sensitive to sounds of different frequencies
frequency theory of pitch perception
nerve impulses sent to the brain match the frequency of the sound wave
Pitch Theory
Combines both Frequency and place theory
Place theory is to ________ as Frequency theory is to ____________.
high frequencies; low frequencies
Amusia
tone deafness
Perfect pitch
Absolute Pitch
auditory cortex
the area of the temporal lobe responsible for processing sound information
Damage to the subcortical area results in
automatic deafness
Nerve Deafness
Hearing loss created by damage to the cochlea,hair cells or the auditory nerve fibers in the inner ear.
Conductive deafness
middle ear deafness
disease or infection it is often structural.
Tinnitus
ringing in the ears, may be a result of nerve deafness
What does mechanical senses respond to?
Pressure, bending & distortion of receptors
otoliths
small crystals in the fluid-filled vestibular sacs of the inner ear that, when shifted by gravity, stimulate nerve cells that inform the brain of the position of the head