Manor Preboards - Module 3

Which of the following situations is most likely associated with Category A medication errors?

a.The presence of SALADs in the hospital formulary.

b.Multivitamin not being ordered on admission for an inpatient.

c.Absence of the use of tall man letters in the pharmacy.

d.Regular release metoprolol was ordered for a patient instead of an extended release preparation.

e.Two of the above

E

Which of the following describes palliative care in cancer patients?

a.Use of chemotherapeutic drugs to eliminate cancer cells

b.Subjecting the patient to radiation therapy

c.Relieve symptoms and pain to improve quality of life

d.Two of the above

C

Patient A, a 48-year-old female weighing 55 kg and with a body surface area of 1.73 m2, has a GFR of 40 mL/min. If patient A has a Serum Creatinine level of 1.5 , what is her creatinine clearance (mL/min) value?

a.46.85

b.35.13

c.39.82

d.23.15

C

If Patient A has a Serum Creatinine level of 1.5, what is her creatinine clearance (mL/min) value?

a.46.85

b.35.13

c.39.82

d.23.15

C

Magnesium sulfate is an inorganic heptahydrate salt also known as Epsom salt. Which of the following is NOT a use of the said compound?

a.Anticonvulsant

b.Antiarrhythmic

c.Antiasthma

d.Antidiarrheal

D

Which of the following drugs cannot be advertised to the general public?

a.Ponstan 500 mg

b.Sinecod 50 mg

c.Cataflam 25 mg

d.Imodium 2 mg

e.Flanax 275 mg

A

Concentration expression most commonly used for suspensions

a.%w/v

b.%v/v

c.%w/w

d.ppm

e.mg%

A

atto denotes ___ of the base unit:

a.10-9

b.10-12

c.10-15

d.10-18

D

DCCXCVI

a.1296

b.796

c.1316

d.896

B

Which of the following is NOT a function of the hospital?

a.Patient Care

b.Wellness

c.Education

d.Research

e.NOTA

E

Medical staff that provide patient services in exchange for training experience

a.Courtesy Medical Staff

b.Associate Medical Staff

c.Consulting Medical Staff

d.Resident Medical Staff

e.Attending Medical Staff

D

DOH Hospital level that requires the presence of a Blood Bank

a.Level 0

b.Level 1

c.Level 2

d.Level 3

D

Hospital supporting service that supplies sterile linen, operating room packs and other medical surgical supplies

a.Nursing department

b.Medical Social department

c.Laboratory Service Department

d.Central Supply Department

D

Emergency drugs are considered as

a.OR drug order

b.STAT order

c.Follow up order

d.AS order

B

Phase of clinical trial that tests drug on healthy volunteers to confirm safety and likely therapeutic dose

a.Phase 0

b.Phase 1

c.Phase 2

d.Phase 3

B

Phase of clinical trial more focused on the performance of an intervention under ideal and controlled circumstances rather than its results under "real world" conditions

a.Phase 1

b.Phase 2

c.Phase 3

d.Phase 1 and 2

e.Phase 2 and 3

B

Which of the clinical trial phases use a subtherapeutic dose?

a.0, 1

b.0 only

c.1 only

d.0, 1, 2

e.1 and 2

A

What study design is illustrated by the following statement:

"A random sample of schools across Luzon is surveyed to assess the prevalence of asthma among elementary students aged 7-9 years old"?

a.Cohort

b.Cross sectional

c.Systematic review

d.Case control

e.RCT

B

How are the following clinical evidence ranked from most to least preferred based on their utility in making clinical decisions?I. Expert opinionsII. Systematic reviewIII. Critically appraised topics and articlesIV. Randomized Controlled Clinical TrialsV. Observational Studies

a.II>III>IV>V>I

b.I>III>II>IV>V

c.II>IV>III>I>V

d.I>II>III>V>IV

A

Any response to a drug that is noxious and unintended, which occurs at a normal dose

a.Adverse Event

b.Adverse Drug Event

c.Adverse Drug Reaction

d.Medication Error

C

Major conjugation reaction in pediatric patients

a.Glucuronidation

b.Oxidation

c.Sulfation

d.Methylation

C

A drug class that have a wide therapeutic range, but is still monitored via TDM because of the toxicity associated with persistently high concentrations and treatment failure with persistently low concentrations

a.Aminoglycosides

b.Carbamazepine

c.Phenytoin

d.Anticancer drugs

e.Theophylline

A

Which of the following is NOT metabolized by N-acetyltransferase 2?

a.Acetaminophen

b.Hydralazine

c.Isoniazid

d.Procainamide

e.Sulfasalazine

A

Steven Johnson syndrome with Toxic Epidermal Necrolysis is a severe skin reaction where macules rapidly spread and coalesce, leading to epidermal blistering, necrosis, and sloughing. Which Hypersensitivity ADR is seen when Sulfonamides cause this cutaneous disease?

a.Type IV

b.Type III

c.Type II

d.Type I

A

Steroids causing Addison's disease is classified under which type of ADR?

a.Type A

b.Type C

c.Type D

d.Type E

D

Which of the following pairs of drug and teratogenic effect is matched correctly?

a.Valproic Acid: genital tract malformation

b.Lithium: abnormal tricuspid valve

c.Methimazole: neural tube defect

d.Alcohol: macrocephaly

e.Warfarin: renal dysgenesis.

B

First line management for pregnant women with GERD

a.PPI

b.H2 Receptor Antagonists

c.Antacids

d.Cytoprotectants

e.Lifestyle changes

E

Patient D.K.'s myasthenia gravis is recently diagnosed and he is started on Mestinon 30 mg three times a day. Upon follow up, he underwent another Tensilon Test to check his treatment response. The administration of Tensilon decreased his muscle strength. What other symptoms may accompany this sudden decrease in muscle strength?

a.Miosis

b.Tachycardia

c.Bronchodilation

d.Constipation

e.Agitation

A

Prothrombic used for minor to moderate bleeding such as that experienced during dental procedures

a.Vitamin K2

b.Tranexamic Acid

c.Aprotinin

d.Aspirin

B

Diuretics are medications used to increase the amount of salt and water expelled from the body as urine. They are often prescribed as antihypertensives, but can be used for other conditions as well. Which of the following pairs incorrectly matches the diuretic class with its indication?

a.Loop diuretics: Pulmonary Edema

b.K+ Sparing Diuretics: Nephrolithiasis

c.Carbonic Anhydrase Inhibitors: Open Angle Glaucoma

d.Osmotic Diuretic: Cerebral Edema

B

Electrolyte imbalance/s characteristic of Digoxin ToxicityI. HypomagnesemiaII. HypokalemiaIII. Hypocalcemia

a.I only

b.II only

c.I, II

d.II, III

C

DOC for Acute Superventricular Tachycardia

a.Magnesium Sulfate

b.Adenosine

c.Calcium Channel Blockers

d.Lidocaine

B

Class of antidepressants with a black box warning of an increased suicidal ideation

a.TCAs

b.SSRis

c.SNRis

d.RIMAs

e.NDRIs

B

Four patients are all managed on Lithium Carbonate for their Bipolar Disorder. Which of these four patients is most likely to experience Lithium toxicity?

a.Patient VX who has cystic fibrosis managed by 10 mL of 4% NaCl inhaled bid

b.Patient RP with catamenial seizures managed via Acetazolamide medication

c.Patient AB who is a recently diagnosed hypertensive put on an initial regimen of hydrochlorothiazide

d.Patient MH, a chronic coffee drinker who drinks at least 5 cups of coffee a day

C

Fever due to endotoxin-like products released by the death of harmful microorganisms within the body during antibiotic treatment

a.Reye's syndrome

b.Jarisch-Herxheimer Reaction

c.Stevens-Johnson Syndrome

d.Nitritoid Reaction

B

How long is a prescription for an antibiotic valid?

a.5 days

b.7 days

c.2 weeks

d.1 month

B

"Take two tablets immediately, then take one tablet every 6 hours for 7 days"

a.tab ii stat tab ss q6h x 7d

b.tab ii prn tab ss q6h x 7d

c.tab ii stat tab i q6h x 7d

d.tab ii prn tab i q6h x 7d

C

Which of the following is not required to be written in a yellow prescription pad when prescribed?

a.Oxycodone

b.Benzodiazepines

c.Barbiturates

d.Methaqualone

e.B, C, and D

E

When this part of the prescription is absent, the written piece of paper is not to be considered a prescription by law.

a.Superscription

b.Inscription

c.Signa

d.Prescriber Information

e.Subscription

A

Specific term for water loss experienced by ointments

a.Crumbling

b.Syneresis

c.Cracking

d.PickingA

A

Only NSAID available in pure S form

a.Ibuprofen

b.Aspirin

c.Naproxen

d.Diclofenac

C

Gelatinization of Acacia mucilage occurs when it is combined with ___

a.Bi

b.Fe

c.Mg

d.Ca

B

What condition can a patient be falsely diagnosed with when Allopurinol interferes with the diagnostic test?

a.Diabetes Mellitus

b.Gout

c.Hyperlipidemia

d.Tuberculosis

e.Leprosy

C

Which of the following statement/s is/are correct about Metronidazole?I. It causes a Disulfiram like reaction when taken with alcoholII. It induces its own metabolism, leading to increased clearance, shortened serum half-life, and progressive serum level decrease.III. When taken with oral anticoagulants, it results to a prolongation of PT.IV. The drug discolors the urine.

a.I only

b.I and IV

c.I, II

d.I, III, IV

D

Which of the following object-precipitant pairs will result to the increased blood serum levels of the object drug?I. Digoxin + WheatII. Quinolones + MilkIII. Ketoconazole + AntacidIV. DMARDs + Penicillamine

a.I only

b.I, III

c.II, III

d.I, IV

A

What type of antagonism is demonstrated by the use of Insulin with Glucocorticoids?

a.Physiologic

b.Pharmacologic

c.Chemical

d.Physical

A

Drug Interaction that may occur but needs more studies

a.Established

b.Probable

c.Unlikely

d.Suspected

e.Possible

D

The following are possible signs of a neutralization reaction EXCEPT

a.Precipitation

b.Evolution of Gas

c.Change or formation of color

d.Photochemical degradation

D

Presence of ___ coloration is an early sign of epinephrine decomposition

a.Pink

b.Brown

c.Green

d.Yellow

A

What pharmacodynamic interaction is demonstrated by concurrent use of Loop Diuretic and Aminoglycoside?

a.Addition

b.Potentiation

c.Synergism

d.Antagonism

C

NSAIDs are known to cause GI irritation. Which of the following solutions is least likely to be done to avoid this side effect?

a.Take NSAID 30 minutes after a meal

b.Add a proton pump inhibitor to the drug regimen

c.Switch to a drug class without GI irritation

d.Replace the drug with Rofecoxib, a selective COX-2 inhibitor.

D

Which of the following are NOT macrovascular complications of DM?I. CADII. StrokeIII. RetinopathyIV. Neuropathy

a.I only

b.I, II

c.III, IV

d.I, III, IV

C

Which of the following instructions is most likely to be seen in the label of Glucobay?

a.Stand in an upright position for at least 30 minutes after taking to avoid irritation.

b.Take one tablet after one bite of meal.

c.Do not take within 3 days of drinking alcohol.

d.Take one tablet during nighttime.

e.Rinse mouth after use.

B

Patient YK, a smoker for 7 years, smokes an average of 12 cigarette sticks daily. How many pack-years has he incurred?

a.4.2 pack years

b.5.6 pack years

c.7.0 pack years

d.8.4 pack years

A

Which of the following Direct Acting Parasympathomimetics can be used for smoking cessation?

a.Pilocarpine

b.Metacholine

c.Varenicline

d.Demecarium

C

Periodic or chronic intoxication that is damaging and caused by repetitive drug use

a.Drug Dependence

b.Drug Habituation

c.Drug Tolerance

d.Drug Addiction

D

In physical examinations, it is the term used to refer to the use of hands to feel for the presence of masses or lumps, tenderness, and texture

a.Light palpation

b.Deep palpation

c.Percussion

d.Auscultation

A

Type of medication error that occurs when a patient receives a drug intended for another patient

a.Omission Error

b.Extra Dose Error

c.Unauthorized Drug Error

d.Wrong Dose Error

C

Methyldopa has an established side effect of depression. What type of ADR is this?

a.Type A

b.Type C

c.Type E

d.Type F

A

In animal studies, amoxicillin has failed to reveal any evidence of teratogenicity. However, there are no controlled data in human pregnancies. What FDA Pregnancy Category does Amoxicillin fall under?

a.Category C

b.Category A

c.Category D

d.Category B

D

Pharmacoeconomic methodology that measures consequences of an intervention through quality adjusted life years

a.Cost of illness Study

b.Cost Benefit Analysis

c.Cost Utility Analysis

d.Cost Minimization Analysis

C

A Philippine Herbal Plant currently being studied for its anti-asthma properties

a.Sambong

b.Banaba

c.Tawa-tawa

d.Pansit-pansitan

C

A low specific gravity of urine is most likely to be a sign of an impairment in which of the following hormones:

a.Oxytocin

b.Vasopressin

c.Insulin

d.Glucagon

B

An increase in this granulocyte signals a hypersensitivity state

a.Neutrophil

b.Basophil

c.Eosinophil

d.Lymphocyte

e.Monocyte

B

Patient HJ shows symptoms of weakness, pallor, and numbness of extremities. During a routine blood test, his blood sample shows that his RBCs are macrocytic and normochromic. He is then diagnosed with a type of anemia. Which of the following tests will most likely confirm the type of anemia experienced by HJ?

a.Coombs Test

b.Schilling Test

c.Oral Iron Absorption Test

d.Bone marrow biopsy

e.Van den Burg Test

B

Assume that Patient HJ tests positive for the suspected type anemia in the confirmatory test, what treatment is he most likely to undergo?

a.Iron supplementation

b.B12 supplementation

c.Folic Acid supplementation

d.Blood transfusion

e.Administration of oxygen

B

Clinical biomarkers elevated in MII. CK-MMII. SGPTIII. TroponinIV. Acid Phosphatase

a.III only

b.I, III

c.I, II, III

d.I, II, III, IV

A

Hypoparathyroidism is associated with

a.Hypercalcemia and hyperphosphatemia

b.Hypercalcemia and hypophosphatemia

c.Hypocalcemia and hyperphosphatemia

d.Hypocalcemia and hypophosphatemia

C

If patient ML's condition goes uncompensated, ___.

a.Administer bicarbonate supplementation

b.Administer Acetazolamide

c.Respiratory Acidosis will succeed the condition

d.Respiratory Alkalosis will succeed the condition

B

Increased urinary recycling decreases elimination rate constant, thus:

a.Half life is decreased

b.Shorter duration of pharmacologic response

c.Increased therapeutic concentration in the body

d.AOTA

C

Enzyme induction of phenobarbital with OCPs can lead to

a.Decreased blood serum levels of phenobarbital

b.Increased action of OCPs

c.Unreliable contraception

d.Two of the above

e.NOTA

C

According to the NYHA, a patient who does not have limitation of physical activity, and in whom ordinary physical activity does not cause undue fatigue, palpitation, or dyspnea

a.Class 0

b.Class 1

c.Class 2

d.Class 3

e.Class 4

B

The amount of minocycline absorbed decreases when combined with which of the following:I. Ferrous Sulfate supplementII. Magnesium Citrate Oral SolutionIII. Kalium DurulesIV. Calcium Carbonate Chewable TabletsV. Maalox

a.I only

b.I, II, III, IV

c.I, II, IV, V

d.I, II, III, IV, V

C

Which of the following is a desirable food-drug interaction?

a.Raw green salads for patients on warfarin DVT prophylaxis

b.Omeprazole beads dispersed in applesauce for patients with difficulty in swallowing capsules secondary to GERD

c.Drinking milk to swallow doxycycline for H. pylori infection treatment

d.Grapefruit juice and cyclosporine to prevent graft rejection

B

Pharmacy division responsible for preparing the pharmacy newsletter

a.Education and training division

b.Drug Information Services division

c.Administrative services division

d.Departmental services division

e.Outpatient services division

B

Which of the following herbs are mismatched with its appropriate therapeutic use?

a.Echinacea: colds and viral infection

b.St. John's Wort: for mild depression

c.Saw Palmetto: BPH

d.Ginkgo biloba: mild sedative

D

Quinupristin + Dalfopristin

a.Synercid

b.Zosyn

c.Primaxin

d.Unasyn

A

The practice of pharmacy that responds to the needs of the people who use the pharmacist's services to provide optimal, evidence based care

a.Pharmaceutical care

b.Good Pharmacy Practice

c.Evidence based medicine

d.Medication use process

B

When dispensing Accutane capsules to females of child-bearing age, what counselling points should be raised by the pharmacist?I. Avoid pregnancy while using the drugII. Discontinue the drug if the acne gets worseIII. Increase exposure to sunlight to help eliminate lesions

a.I only

b.I and II

c.I and III

d.I, II and III

A

Bisacodyl interacts with milk through what mechanism

a.Complexation

b.Adsorption

c.Alteration of pH

d.Alteration of motility

C

Mixtures of phenolics, aldehydes, and ketones are examples of

a.Immiscible substances

b.Hygroscopic substances

c.Deliquescent substances

d.Eutectic mixtures

D

The extent to which a technique consistently measures whatever it measures regardless of the investigator of the experiment

a.Dependability

b.Vulnerability

c.Reliability

d.Validity

C

Which of the following acronyms refer to parenteral nutrition?

a.TPN

b.TNA

c.PMN

d.Two of the above

e.AOTA

D

Solubility of a substance may be expressed in several ways. When a quantitative statement of solubility is given in the USP it is generally expressed as:

a.g of solute soluble in 1 mL of solvent

b.g of solute soluble in 100 mL of solvent

c.mL of solvent required to dissolve 1 g of solute

d.mL of solvent required to dissolve 100 g of solute

C