upper GI medchem
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Last updated 10:51 AM on 3/25/26
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14 Terms
1
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what are the 3 binding regions for the H2 receptor
imidazole ring binding region
agonist binding region
antagonist binding region
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what are the 2 polar binding regions of the H2 receptor
agonist binding region
antagonist binding region
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what can only reach the polar agonist region in histamine
charged alpha nitrogen
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what can histamine only bind as
an agonist
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why does an isothiourea group decrease antagonist activity compared to increased antagonistic activity a guanidine group
sulfur doesnt get involved in the resonance delocalisation so positive charge is further away
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