All about the eyes

How does Oxygen therapy lead to ROP?

Oxygen inhibits normal retinal vascular proliferation leading to retinal detachment and sometimes blindness. Use of oxygen increases damaging reactive oxygen species

At what gestation is most common

Babies born less than 28 weeks gestational age

What are the top three PRIMARY risks factor for ROP

Prematurity, low birth weight, postnatal oxygen exposure

Wha other factor or prematurity contributes to ROP

• They have fewer antioxidants to counteract ROS (rEACTIVE OXYGEN SPECIES)

• this LEADS TO ENDOTHELIAL CELL DAMAGE, APOPTOSIS AND CAPILLARY CONSTRICTION

What are some secondary risk factors in development of ROP?

• Hyperoxia

• Apnea

• Sepsis

• Blood transfusion

• Antioxidant deficiency

• PDA

• Infection of the intestine

• IVH

What are the criteria for screening for ROP in the NICU

• < 31 WEEKS

• Weigh less than 1250g at birth

What do we classify as zones?

Zones describes how far the blood vessels have grown away from the optic nerve. Zone 3 means the blood vessels have grown away from the nerve and closer to the retina

What does stages mean?