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excitatory neurotransmitter
glutamate
inhibitory neurotransmitter
GABA
decorticate
flexed arms → better prognosis
hands to your CORE
decerebrate
extension and pronation→ bad prognosis
which lobe: emotions and motor
frontal
which lobe: language, hearing, smell, short term memory
temporal
which lobe: astereognosis, hemispatial + sensory
parietal
which lobe: visual
occipital
which aphasia: talks nonsense, pt unaware
wenicke's → Nickie's nonsense
which aphasia: broken speech, aware
broca's → Bro Can't talk
order of consciousness
alert → lethargic→ obtundation→ stupor→ coma
weakness, easy fatiguability, normal sensation, tongue fasciculation
ALS → need muscle biopsy
NO sensory loss
motor UMN and LMN destruction
ALS
pain/paresthesia in 1st 3 digits and radial 1/2 of 4th, worse at night
carpal tunnel syndrome → phalen and tinel
median nerve
multifocal asymmetric demyelination of white matter in CNS
MS
dawson's fingers on MRI
MS
Oligoclonal bands in CSF
MS
viral infection causing destruction of anterior horn cells
polio
ascending paralysis
GBS
unchecked excitatory impulses
tetanus → tetanus IG
symmetric descending paralysis
botulism
blockage of neuromuscular transmission at the ach post-synaptic receptors
myasthenia gravis → MC in young females
muscular weakness worse in evening, extraocular symptoms like ptosis and diplopia
MG → tensilon test (improved grip within 30 secs)
gait ataxia, ophthalmoplegia, confusion
wenicke's encephalopathy → givre thiamine
pt doesn't allow knee extension when hip is flexed
kernig's
pt resists passive flexing of chin to chest
brudzinski
MCC encephalitis in US
HSV/VZV → acyclovir
b-amyloid plaques, neurofibrillary tangles, cortical atrophy
alzheimer's
dementia with parkinsonian features, hallucinations, delusions
lewy body dementia
stepwise progression of deficits
vascular dementia → lacunar infarcts
seizure without LOC
simple partial
seizure with mild LOC and an aura
complex partial
seizure appearing as daydreaming in childhood
absence → ethosuximide
seizure >5 mins
status epilepticus → give benzos
sudden LOC, rigid and fall to ground, jerking, tongue biting, incontinence, post ictal confusion
tonic clonic seizure
tumor causing bitemporal hemianopsia
prolactinoma → bromocriptine
worst HA of my life
SA → head CT w/o contrast
POUND mnemonic for migraines
Pulsatile (throbbing)
Onset/duration (4-72 hours)
Unilateral in location
Nausea and vomiting
Disabling in intensity
migraine with aura
classic migraine
migraine without aura
common
migraine prophylaxis
Propranolol, topiramate, amitriptyline
unilateral HA with tearing
cluster → give 100% O2
prophylaxis for cluster HA
verapamil
bilateral bandlike HA
tension
saddle anesthesia, bladder/bowel dysfunction, gait disturbance
cauda equina→ stat MRI and neuro consult
discriminative touch, vibration, proprioception
posterior white column (Gracilis and cuneatus)→ crosses over at medulla so ipsilateral defects
light touch and pressure
anterior white column → crosses at spine so contralateral defects
pain and temperature
lateral spinothalamic tract → crosses at the spinal cord so contralateral defects
positive kernigs and nuchal rigidity, headache
SAH
tremor at rest, rigidity, akinesia, postural instability
parkinson's
onion peel on xray
Ewing's sarcoma
pain out of proportion s/p surgery/injury
CRPS
conjunctivitis, urethritis, oligoarticular arthritis
reactive arthritis → can't see, can't pee, can't climb a tree
chondrocalcinosis
pseudogout (CPPD) → weakly positive, birefringent rhomboid crystals
-1 to -2.5 T score
osteopenia
-2.5 T score
osteoporosis
spinal tuberculosis
Pott's disease
gold standard to acute osteomyelitis dx
open biopsy and bone aspiration
erythema migrans (bullseye), fever, fatigue, recently camped
lyme dz → doxy
amox for kids
XR: lost joint space, sclerosis, subchondral cysts, osteophytes
osteoarthritis → deformity in weight bearing joints
lower back pain worse in AM, uveitis, bamboo spine, +HLA-B27
ankylosing spondylitis → sacroilitis is hallmark
young woman, generalized pain in multiple trigger points, spared joints, anxiety/depression, memory problems
fibromyalgia → sx >3 months in 4 quadrants
salter harris..........................
....................
schmorl's nodes, poor posture, tight hamstrings, M>F
scheuermann's kyphosis
scoliosis treatment
10-25 degrees = PT and monitor
25-45 degrees = brace/PT
>45 degrees = surgery and PT
dissolution or loosening of pars interarticularis
spondylolysis
bilateral = spondylolisthesis
slipped disc
Spondylolisthesis
partial spinal cord transection
Brown-Sequard syndrome → early high dose methylpredniosolone
UMN or LMN: flaccid paralysis, weakness, decreased tone
LMN
UMN or LMN: spastic paralysis, hyperreflexia, +babinski
UMN
which hip dislocation: flexion, IR, ADDuction
posterior → fem head appears smaller on XR
which hip dislocation: mild flexion, ER, ABduction
anterior→ fem head appears larger on XR
causes of avascular necrosis
- fall/trauma
- alcoholism
- long term steroid use
MC fracture of child abuse
long bone shaft
spiral fracture is common
hair on end appearance, sunray burst apperance
osteosarcoma → mc primary bone tumor common in teens
which test: radiating pain indicates nerve root compression
spurling → axial load
head tilted toward affected side, rotated towards unaffected side, SCM lump, cranial/facial asymmetry
torticollis
what XR is used for cervical trauma pts
cross table lateral xray
young boy, limp/trendelenburg gait, mild pain, atrophy of thigh/calf/butt, leg length inequality
legg-calve Perthes disease → avasc necrosis of femoral head
activity restriction, long leg bracing, surgery
groin pain, decreased internal rotation, trendelenburg gait, kline's lines, ice cream falling off cone, pistol grip deformtiy
SCFE → progressive displacement of upper portion of femur
male adolescents!
MCC compartment syndrome
tibia fracture → fasciotomy is the tx
gradual onset pain in anteromedial aspect of distal 1/3 leg, pain with plantar flexion/inversion, pain with heel walking
shin splints → develops from exercise
unhappy triad
ACL
MCL
Meniscus
meniscal tear MOI
Knee flexion with rotational stress while weight bearing.
Most sensitive test for ACL tear
Lachman's test
PCL injury MOI
knee forced posteriorly → MVA, blow to the knee
+ valgus stress test
MCL injury
+ varus stress test
LCL injury
MC patellar dislocation
lateral
RF = excessive Q angle
why do you need to check pulses in tibiofemoral dislocations?
bc complication is popliteal artery injury → stat vascular consult
teen boy/young man athlete, pain and swelling in anterior knee
osgood schlatter
pain behind knee
patellofemoral syndrome → dull aching pain, +apprehensive and ober test
pain in the AM with 1st step
plantar fascitis
pain and tenderness over base of 5th metatarsal d/t inversion injury
jones fracture
playing sports, felt a pop, can't stand on tiptoes on affected side. positive thompson's test
achilles rupture → plantar flexion is absent→ surgical repair
aching, burning pain in lateral elbow from repeated extension, decreased pain at rest.
lateral epicondylitis → tennis elbow
aching, burning pain in medial elbow from repeated flexion
medial epicondylitis → golfer's elbow
annular ligament entrapment and radial head subluxation
nursemaid's elbow → from pulling/swinging child's arm
dislocation of radial head and fx of proximal 1/3 ulna
monteggia fracture
radial shaft fracture and dislocation of distal radioulnar joint
galeazzi fracture→ requires surgery