Galens 4 humours
blood, phlegm, yellow bile and black bile
need to be in balance for good health
followed as it made sense of symptoms at the time
medieval ideas about causes of illness
punishment from God
bad air
astrology / superstition
unbalanced humours (common)
how to fix an illness that was a punishment from god (medieval)
prayers and herbal remidies
blessing / asking for forgiveness
how to fix an illness caused by miasma (medieval)
filth in streets removed e.g. 1349 plague slowed by Mayor asked by king to remove dirt in streets
how to fix an illness cause by unbalanced humours
unrine charts
bloodletting
purging
trepaning (get rid of demons)
physicians (medieval)
highest ranking doctors
well paid - treated kings
very few
wise women (medieval)
most common
remedies and superstition
midwives
did everyhting
barber sugerons (medieval)
most common
blood letting and tooth extraction
guild of master surgeons
trained by apprenticeship
how did islamic golden age progress medicine?
hospitals in Cairo and Bhaghdad
crusades spread islamic knowledge into west europe
books translated into latin and spread
Avicenna ‘Canon of Medicine’ book described 700 drugs some still used today
new diseases / developments due to Islamic golden age?
pulmonary circulation discovered
vaccination 50y pre Jenner
parasites described in 1100s, questioning Galen
alchemy invented so new drugs
christianity helped development of medicine (medieval)
people could learn from Greek / Roman ideas - not all knowledge lost
church controlled unis - every doctor thought the same
hospitals to look after poor / elderly - not sick
christianity hindered development of medicine (medieval)
knowledge didn’t change and ideas were not questioned
taught to follow Galen + not question - banned any deviation and human dissection
if God sent diseases then u couldn’t fix it, disease as proof of god and cure as miracles
anaesthetics (medieval)
mandrake root
opium
hemlock
whiskey
surgical procedures (medieval)
bloodletting
amputation
cauterisation
people with ideas (medieval)
Galen most widely supported
Hugh of Lucca and Theodoric - some good ideas e.g. wine on wounds to reduce infection but didn’t support Galen so was cancelled
De Chauliac - famous textbook (Great Surgery 1363) dominated surgical knowledge for 200 years
public health in towns (medieval)
generally bad
towns near to rivers (waste and water supply)
cesspits - not emptied regularly so would leak into river
no knowledge of germs, but removed unpleasant smells
some local laws to keep towns clean but nothing huge
places with good public health in medieval era?
isolated places as disease didnt spread
monks - water very important
monasteries were wealthy from money for prayers
monks had access to medial books, and learned sanitation from Greeks/Romans
what did people think caused Back death
postion of stars
miasma
jews poisoning wells
god punishing people
what actually caused black death
bubonic and pnuemonic plagues
pneumonic infected lungs - more infectious
when did Black death hit england
1348-49
what did the black death affect
both rich and poor
towns and ports hit worst
preventions for black death (medieval)
strangers not allowed into villages
prayers
mayor asked to clean london up by kind edward 3
huge candles lit in streets (miasma)
doors and windows shut and sealed
treatment for Black Death (medieval)
prayers
holy charms around neck of sick
let pus out of buboes
leches to bleed patients
based on Galen’s theory of opposites
Short term impact of Black Death (medieval)
killed 1/3 of popp.
whole villages wiped out
food shortages - food prices increased
long term impact of black death (medieval)
higher wages for workers
higher education levels
peasants revolt
hospitals in medieval times
like todays care homes
not for sick only for elderly
had hospitals in ancient Arabia like today
how did people know about anatomy (medieval)
Galen, Hippocrates, Arabs
dissections to prove Galens ideas
doctors not encouraged to make new discoveries
Vesalius discoveries and action
dissected criminals for anatomy knowledge
proved Galen wrong (breatbone 3 parts not 7)
wrote the book ‘Fabric of the Human Body’
first book on anatomy
short-term impact of Vesalius
improved knowledge about anatomy in Europe
changed attitudes
changed training
triggered research into anatomy
long-term impact of Vesalius
traditional ideas challenged (Renaissance)
Pare and Harvey
discovery and experience encouraged not textbook
focus on enquiry
limitations of Vesalius’ work
no one was healthier
doctors still basing treatments off Galen
ideas didnt spread to everyone and lots of criticism
was it technology w printing press in 1451 not individual?
why did medicine change in renaissance?
move away from religion, people ignored church’s medical advice, Galen’s ideas beginning to be questioned
rediscovery of classic ideas e.g. Avincenna
printing press 1451 allowed ideas to spread
more people could afford education and experiments encouraged.
consequences of renaissance
new learning w observation, experimentation
inventions - gunpoweder meant new wounds meant new wounds to treat
americas discovered so new medicines
new art style so human body more realistic
ideas spread faster w printing press
Harvey discoveries
circulation
through dissection and experiments
one way system for blood and proved Galen wrong
Harvey short term impact
ignored
v little impact
50 years before ideas accepted and taught (microscopes for capillaries)
was the first to provide actual proof of this via empirical evidence
Harvey long-term impact
turning point in history for med
how poisons could spread through body
part of disproving Galen’s theories e.g. 4 humours
scientific rev in C17 and C18 towards practical working and dissection
long term in blood transfusions and that in ww1
Harvey limitations
couldnt explain all of it as microscopes werent invented so couldn’t see capillaries
couldn’t explain anything
didnt help day to day health of people
Pare actions and discoveries
used turpentine, egg white and cream of rose oil instead of boiling oil to treat gunshot wounds
ligatures not cauterization
pare short-term impacts
challenged accepted ideas about wounds (not poisonous)
translated Vesalius book into French so increased knowledge of anatomy in Europe
Clowes (surgeon to Queen liz 1) inspired by him
Pare long term impacts
Clowes
English version of Vesalius’ work printed in 1634
Pare limitations
just luck?
ligatures had been used by Galen before and infected wounds
Public health in C17 and C18 (renaissance)
still poor
had barber-surgeons, apothecaries, wise women, quacks, and bloodletting
printing press allowed people to get books on herbal remedies
towns still filthy
lots of wars which took money away from public health
popp increasing so more strain on public health systems e.g. water supplies + sewers
When was the Great plague
1665
killed 100,000 in London
Causes of Great Plague believed at the time
miasma
punishment from God
movement of planets
similar to Back Death
Cures to Great PLague
no cure
smoke to keep away poisoned air
awareness of dirt ad disease being connected
Measures taken to defend against Great Plague
rich moved away
mayors issuing quarrantine orders to stop spread
women searchers to identify those with disease
plague victims quarantined
red cross painted on infected houses
trade between town stopped and scottish border closed
How did Great Plague end
not in Great fire of London 1666, as fire didnt reach poorest parts ouside city walls
rats developing resistance to disease so fleas didnt need human hosts
Hospitals in renaissance period C17 and early C18
hospital boom began
modern hospitals w modern medicine but not large understanding of sanitation ect.
built by community or rich people (dissolution of monasteries gave money)
treatments based on 4 humours
medical schools attached to hospitals
attitudes towards poverty shifted as Christians wanted to be more active in helping others
John Hunter overview
1728-93
scientific methods importance for research
specimen collection - anatomy
John Hunter books
Gun shot wounds - shouldnt be made larger but treated as any other wound (radical)
widely read and major contribution to surgical knowledge
discoveries on nature of disease, infections, cancer and circulation
John Hunter scientific techniques
syphilis and gonorrhoea guy
promoted careful observation and scientific method
Hunter short term significance
not very - percieved as a villain due to grave robbing
first transplants on chickens
taught others e.g. Jenner
scientific techniques
Hunter long term significance
encouraged more scientific approaches to anatomy and surgery
books translated and read all over europe
influenced Jenner
how dd royal society help develop medicine
royal charter granted in 1660, gave them credibility and people donated money / sent works for publishing
more money and less dependence on patrons meant tech and equipment was hi tech and could be used for experimenting
copy of every scientific journal preserved in english so could be spread across europe
Royal College of surgeons / barber surgeons
Henry 8 allowed company of barber-surgeons to be formed in 1540
maintained standards and qualifications
1746 surgeons wanted to be seen as superior so separate college created for them
inoculation beginnings
medieval chine and asia using basic inoculation to prevent smallpox
became profitable in 1700s england
however some ha religious objections, poorest couldn’t afford, inoculated could still carry and spread, and too large a dose could kill people
Jenner dscovery
milkmaids if had cowpox didnt get small pox worked on 8yr boy
called it vaccination
published in 1798
Opposition to Jenner
couldnt really explain it
wasnt accepted by other doctors
snobbery as Jenner was from country
would lose money from innoculation
Jenner short term impact
revolutionary? and potential to save lives
important bc 30% small pox mortality rate
however was shunned, peer assessors used contaminated equipment, couldnt explain it bc germ theory not until 1861
Jenner long term impact
royal family vaccination raised support
eradication of smallpox - massive step for medicine
vaccination central to fight against disease as medicine developed
1861 germ theory and Kochs microbes allowed Jenner’s work to be adapted e.g. covid -19
pain relief origins
used since medieval period e.g opium
had to do surgeries quickly to avoid blood loss
difficult to judge doses
Nitrous oxide as pain relief
fairground attraction
1795 in UK
1844 Wells used in in US in tooth extraction
wasnt convincing
Ether as Pain relief
1842 Clark used in tooth extraction
effective anaesthetic
spread to UK with Liston
dangerous as was difficult to inhale, cause vomiting and flammable and many patients had surgery by fires at home
Chloroform as pain relief
discovered in 1847
by James Simpson
dangerous if dose was incorrect
Opposition to Pain relief in C19
doctors used to operating quickly on conscious patients
e.g. Crimean war docs thought soldiers should put up w pain
religious objections
overcome by Queen Vic using chloroform in childbirth in 1853
importance of development of pain relief
step forward however didnt revolutionize surgery
still v high death rate from surgery and infection
hospital infections
belief about causes of infection in 19th century
thought infections were chemical reactions
if wound became infected would cauterise or burn away w acids
spontaneous generations
microbes viewed but no link between microbes and disease
thought all microbes were the same and disease caused microbes
some questioning of ideas but no proof
louis pasteur experiment
swan necked flask and milk
if air kept out of flask, liquid wouldnt go off
proved that germs didnt come alive on their own but infected things they could reach
proved bacteria caused disease and it was biological not chemical
when was Germ Theory published
1861
by Pasteur
Pasteur short term significance
theory of miasma long standing
belief that small microbes couldnt harm large humans
Jenners vaccination
some opposition
in france not england
Pasteur long term significance
basis of understanding of disease today
bacteriology
Koch and Pasteurs work bringing hope of vaccination and eradication of disease
some vaccination made mandatory by gov in coming decades
anti-contagionism vs contagonism
anti: epidemics caused when infections interacted w environments and created the disease
vs infections spread by contact w infected person/ bacteria
what did Lister do
1860s
operations went well as long as wound was free of infection
used carbolic acid to kill bacteria
only irritation was due to carbolic acid
antiseptic techniques
reaction of Lister’s work
publicised Germ Theory in UK
criticised in Uk as was controversial to say that infection was caused by microbes in the air and not spontaneous generation or miasma
why did people oppose Lister’s method?
didnt accept Germ theory in britain
antiseptic already widely used and not revolutionary
often difficult and unpleasant to use his methods
still couldnt fully explain it
didnt wash hands before surgery and operated in street clothes
lister short term significance
mostly insignificant
incomplete ideas
huge amount of opposition
germ theory not yet accepted
carbolic acid expensive
lister long term significance
45% death rate decrease
increased life expectancy
helped catalyse acceptance for germ theory
forms the basis of disease and medical treatment
aseptic surgery
microbes excluded fro surgery from the start
surgeons well scrubbed, wearing gowns, using sterilised equipment
huge public operating theatres replaced w smaller rooms
reduced no. or infections
depended of accepting germ theory
what did Koch do?
found a way to stain and grow a particular germ
changed study of bacteria
prove a specific bactera responsible for a specific disease
discoveries into typhoid, tetnus, meningitis