antimicrobial substances

interferons

Secreted by viral infected lymphocytes, macrophages, and fibroblasts, Stimulate healthy tissue cells to produce an antiviral protein, Stop/slow down viral replication

complement system/proteins

Plasma proteins built by hepatocytes, after being activated, enhance immune responses: attract phagocytes, stimulate release of histamine, promote phagocytosis, some can directly cause cytolysis of microbes

iron-binding proteins

Inhibit bacterial growth by binding and removing iron from sites of infection

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