Drug receptors

what are the 2 major classifications of drug receptors

• ionotropic

• metabotropic

what classification of receptors utilized 2nd messengers and has a slower onset of action

metabotropic

what are the 4 major types of receptors

1. ion channel

2. GPCRs

3. enzyme linked

4. intracellular

what are the 3 subtypes of G protein couple receptors

• GS

• GI

• GQ

Unlike other receptors the ______________ are transmembrane

enzyme linked receptors

enzyme linked receptors form ______ and activate enzymes on the other side of the plasma membrane

heterodimer

what are 4 types of activity drugs can have within the body

• agonist

• antagonist

• partial agonist

• inverse agonist

a drug that binds somewhere else entirely but still inactivates the an effect is known as a _____________

non competitive antagonist

the force of attraction between drug and receptor is known as __________

affinity

a drugs ability to affect a particular receptor population in preference to others refers to its _____________

selectivity

efficacy is the innate maximum ________ a drug can have on a body

response

decreasing potency means that you need _____ drug to get a ________ resposne

• more

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