Excitation-Contraction Coupling (ECC)
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Last updated 4:44 PM on 10/28/25
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6 Terms
1
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First step of ECC
• Action potential travels along sarcolemma → down T-tubules.
2
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Second step of ECC
• Signal triggers sarcoplasmic reticulum (SR) to release Ca²■.
3
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Third step of ECC
• Ca²■ binds to troponin, moving tropomyosin off actin binding sites.
4
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Fourth step of ECC
• Myosin binds to actin → cross-bridge cycle starts.
5
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Fifth step of ECC
• When stimulation ends → Ca²■ pumped back into SR.
6
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Sixth step of ECC
• Troponin-tropomyosin block returns → muscle relaxes.
Note 
Flashcards (40)