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Levodopa/Carbidopa (Sinemet)
Indications
Help PT improve their day-to-day activities and daily living
Levodopa/Carbidopa (Sinemet)
ADEs
Nausea
vomiting
dyskinesias (involuntary movement)
Interferon Betas (Multiple Drugs)
Class
TC
Drugs for MS
PC
Immunomodulator (disease-modifying drug)
Interferon Betas (Multiple Drugs)
ADEs
Flu-like symptoms
hepatotoxicity
depression
Mitoxantrone (Novantrone)
Indication
Treat MS and cancer
Mitoxantrone (Novantrone)
Class
TC
Drug for MS
PC
Immunosuppressant
Phenytoin (Dilantin)
MOA
blocks Na+ from entering the neurons causing AP to be diminished
Phenytoin (Dilantin)
Administration
PO
IV
IM
Anti-Epileptics Drug Class
PT Education
signs of precede suicidal behavior
women to take folic acid supplements before and throughout pregnancy
Anti-Epileptics Drug Class
Nursing Implications
Monitor plasma drug levels
Baclofen (Lioresal)
MOA
acts in spinal cord to suppress hyperactive reflexes
can mimic the actions of GABA on spinal neurons
Haloperidol (Haldol)
MOA
blocks dopamine2 receptors & minimize symptoms of psychosis
able to block acetylcholine, histamine, & NE
Haloperidol (Haldol)
ADEs
orthostatic hypertension
sedation
Clozapine (Clozaril)
MOA
blocks D2 dopamine receptors
affinity for these receptors are low
blocks receptors for NE (alpha 1), histamine and acetylcholine
Fluoxetine (Prozac)
Class
TC
Antidepressant
PC
SSRIs
Venlafaxine (Effector XR)
MOA
blocks NE and 5-HT reuptake
weak blockade of dopamine
Phenelzine (Nardil)
MOA
inhibits MAO-A in nerve terminals causing drugs to increase amount of NE and 5-HT available for release
Lithium (Lithobid)
Class
TC
Drugs for bipolar disorder
PC
mood stabilizer
Lithium (Lithobid)
Indication
helps manage manic episodes in PT w BPD
Lithium (Lithobid)
Toxicity
Drug range 0.4 - 1 mEq/L
Diazepam (Valium)
MOA
strengthens the effect of GABA has on the body and limit the CNS depressant it can have
Diazepam (Valium)
ADEs
CNS depression
Respiratory depression
Buspirone (BuSpar)
MOA
high affinity to serotonin receptors
low affinity to dopamine receptors
Buspirone (BuSpar)
Indication
GAD
Panic disorder
OCD
PTSD
Methylphenidate (Ritalin)
Indication
reduce ADHD symptoms in children and adults
reduce sleep attacks in PT w narcolepsy
Methylphenidate (Ritalin)
Schedule
Schedule II
Methylphenidate (Ritalin)
ADEs
Restlessness
Insomnia
Weight loss
CV effects