NURS 472A Exam 3 Week 9

Levodopa/Carbidopa (Sinemet)

Indications

Help PT improve their day-to-day activities and daily living

Levodopa/Carbidopa (Sinemet)

ADEs

• Nausea

• vomiting

• dyskinesias (involuntary movement)

Interferon Betas (Multiple Drugs)

Class

• TC

  • Drugs for MS

• PC

  • Immunomodulator (disease-modifying drug)

Interferon Betas (Multiple Drugs)

ADEs

• Flu-like symptoms

• hepatotoxicity

• depression

Mitoxantrone (Novantrone)

Indication

Treat MS and cancer

Mitoxantrone (Novantrone)

Class

• TC

  • Drug for MS

• PC

  • Immunosuppressant

Phenytoin (Dilantin)

MOA

blocks Na+ from entering the neurons causing AP to be diminished

Phenytoin (Dilantin)

Administration

• PO

• IV

• IM

Anti-Epileptics Drug Class

PT Education

• signs of precede suicidal behavior

• women to take folic acid supplements before and throughout pregnancy

Anti-Epileptics Drug Class

Nursing Implications

Monitor plasma drug levels

Baclofen (Lioresal)

MOA

• acts in spinal cord to suppress hyperactive reflexes

• can mimic the actions of GABA on spinal neurons

Haloperidol (Haldol)

MOA

• blocks dopamine2 receptors & minimize symptoms of psychosis

• able to block acetylcholine, histamine, & NE

Haloperidol (Haldol)

ADEs

• orthostatic hypertension

• sedation

Clozapine (Clozaril)

MOA

• blocks D2 dopamine receptors

  • affinity for these receptors are low

• blocks receptors for NE (alpha 1), histamine and acetylcholine

Fluoxetine (Prozac)

Class

• TC

  • Antidepressant

• PC

  • SSRIs

Venlafaxine (Effector XR)

MOA

• blocks NE and 5-HT reuptake

• weak blockade of dopamine

Phenelzine (Nardil)

MOA

inhibits MAO-A in nerve terminals causing drugs to increase amount of NE and 5-HT available for release

Lithium (Lithobid)

Class

• TC

  • Drugs for bipolar disorder

• PC

  • mood stabilizer

Lithium (Lithobid)

Indication

helps manage manic episodes in PT w BPD

Lithium (Lithobid)

Toxicity

Drug range 0.4 - 1 mEq/L

Diazepam (Valium)

MOA

strengthens the effect of GABA has on the body and limit the CNS depressant it can have

Diazepam (Valium)

ADEs

• CNS depression

• Respiratory depression

Buspirone (BuSpar)

MOA

• high affinity to serotonin receptors

• low affinity to dopamine receptors

Buspirone (BuSpar)

Indication

• GAD

• Panic disorder

• OCD

• PTSD

Methylphenidate (Ritalin)

Indication

• reduce ADHD symptoms in children and adults

• reduce sleep attacks in PT w narcolepsy

Methylphenidate (Ritalin)

Schedule

Schedule II

Methylphenidate (Ritalin)

ADEs

• Restlessness

• Insomnia

• Weight loss

• CV effects