Alzheimers

An effect on communication, metabolism, and repair of neurons leading to neuron death

What is Alzheimer’s

Inherited occurring before 60

What is considered early onset Alzheimer’s

Sporadic occurring after 60

What is considered late onset Alzheimer’s

Beta amyloid, hyperphosphorylated Tau protein, and cholin acetyltransferase deficiency

What are the many causes of Alzheimer’s

Accumulate into senile plaques that are neurotoxic and stimulate immune response damaging neurons

How does beta amyloid cause alzheimers

Senile plaques

What initiated the development of alzheimers

Accumulate into neurofibrillary tangles in pyramidal neurons causing dysfunction, death, immune reaction, and loss of microtubule stabilization

How does hyperphosphorylated Tau proteins cause alzheimers

Occurs in the basal forebrain and affects memory and attention

How does choline acetyltransferase deficiency cause alzheimers

Short term memory loss

What is the first sign of alzheimers

High senile plaques and neurofibrillar tangles

What contributes to severe alzheimers

Difficulty with learning, cognitive issues, memory, behavioral changes, agitation, and psychosis

What are the symptoms of alzheimers

Small, ventricular enlargement (hydrocephalus ex vacuo)

What does a brain with alzheimers look like