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Inspiration
The process of air flowing into the lungs; diaphragm and external intercostal muscles contract.
Expiration
Air leaves the lungs; diaphragm and external intercostal muscles relax.
Diaphragm
A dome-shaped muscle that contracts during inhalation to help lungs expand.
Intercostal Muscles
Muscles between the ribs that assist in expanding and contracting the chest cavity during breathing.
Medulla & Pons
Brainstem areas that control breathing rhythm (the “pacemaker” of respiration).
Eupnea
Normal breathing rate (12–15 respirations per minute).
Hyperpnea
Deep or forceful breathing, often during exercise.
Pulmonary Ventilation
Movement of air into and out of the lungs; also known as breathing.
External Respiration
Gas exchange between the alveoli and the blood in pulmonary capillaries.
Respiratory Gas Transport
Oxygen and carbon dioxide are transported by the bloodstream to and from tissues.
Internal Respiration
Gas exchange between the blood and tissue cells.
Air-blood Barrier
The thin membrane where the alveolus and capillary meet, allowing gas exchange.
Simple Diffusion
Passive movement of gases (O₂ and CO₂) across the air-blood barrier based on concentration gradients.
Macrophages (in lungs)
Immune cells that defend the alveoli from pathogens and particles.
Lung Surfactant
Substance produced by alveolar cells to reduce surface tension and keep alveoli open.
Asthma
A respiratory disorder where airways are overly sensitive and inflamed, leading to difficulty breathing.
Chronic Bronchitis
Ongoing inflammation of respiratory mucosa that causes excessive mucus production.
Emphysema
Chronic lung condition where alveolar walls are damaged, reducing gas exchange and elasticity.
COPD
Chronic Obstructive Pulmonary Disease – a group of disorders (asthma, chronic bronchitis, emphysema) that obstruct airflow.