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Arteries carry blood ____ from the heart
away
Microcirculation
Process where nutrient and gas exchange occurs.
Arterioles
Small blood vessels supplying capillaries.
Capillaries
Tiny vessels facilitating exchange with tissues.
Venules
Small vessels collecting blood from capillaries.
Veins
Blood vessels returning blood to the heart.
The vital functions of the cardiovascular system take place at the ______
capillary level
Chemical and gaseous exchange between the blood and interstitial fluid takes place across_____
capillary walls
Why does tissue cells rely on capillary diffusion?
It obtains nutrients and oxygen to be able to remove metabolic waste such as carbon dioxide and urea.
Blood flowing out of a capillary bed first enters structures called ________.
Venules, the smallest vessels of the venous system
Venules, slender vessels merge to form small___
veins
Tunica interna
Innermost layer, directly contacts blood.
Tunica media
Middle layer, composed of smooth muscle.
Vasoconstrict
Narrowing of blood vessels, increases pressure.
Vasodilate
Widening of blood vessels, decreases pressure.
Tunica externa
Outer layer, made of loose connective tissue.
Largest arteries, closest to the heart.
Systole
Phase when heart contracts, arteries stretch.
Diastole
Phase when heart relaxes, arteries recoil.
Muscular arteries
Medium-sized arteries, regulate blood flow.
Arterioles
Tiny branches of arteries, lead to capillaries.
Capillary networks
Microcirculation sites for nutrient exchange.
Elastic arteries during ventricular systole do what?
stretch
Elastic arteries during ventricular diastole do what?
Recoil
Muscular arteries distribute blood to?
Skeletal muscles and internal organs
Large vein
superior and inferior vena cava and their branches within the abdominopelvic and thoracic cavities
Medium-sized vein
The tunica media in these veins is thin, and contains few smooth muscle fibers
Venule
small vein, collect blood from capillaries, lack a tunica media
What kind of arteries are the pulmonary trunk and aorta?
elastic arteries
The tunica media of elastic artery contain few______compared to____
smooth muscle fibers, elastic fibers
Muscluar arteries have a thick___
tunica media
What does the muscular artery contain more percentage than elastic fibers?
smooth muscle fibers
Arteriole vessels are much____than muscular arteries
thinner
What does the arteriole poorly have defined?
Tunica externa
What does the arteriole vessel tunica media consist of?
scattered smooth muscle fibers that may not form a complete layer
Capillaries are the only blood vessels whose walls permit?
exchange between blood and the surrounding interstitial fluid.
Most substances enter or leave the capillary by______across endothelial cells or through gaps between them.
Diffuse
What material can easily diffuse into the surrounding interstitial fluid?
Water, small solutes, and lipid-soluble
Capillaries do not function as individual units. Instead, they function as part of an interconnected network called a
Capillary bed
Capillaries collect into several_____, the smallest venous vessels
venules
What are the smallest venous vessels?
venules
What band of smooth muscle, guards the entrance to each capillary?
Precapillary sphincter
Each precapillary sphincter undergoes________of______, alternately contracting and relaxing perhaps a dozen times each time.
Cycles, activity
What is vasomotion?
The cyclical contraction and relaxation of precapillary sphincters, causing intermittent blood flow in capillaries.
How does blood reach venules in different ways over time?
Due to vasomotion, blood flow is not constant but varies based on the contraction and relaxation of precapillary sphincters.
what triggers changes in blood flow at the tissue level?
Local changes in the concentration of chemicals and dissolved gases on the interstitial fluid
What is the process of local blood flow control at tissue level called?
Autoregulation
What are the five general classes of blood vessels?
Arteries, arterioles, capillaries, venules, and veins.
What typeof vessel are small, thin-walled, and have very little smooth muscle in the Tunica media
Capillaries
Why are valves found in veins but not in arteries?
Valves are found in the veins because the very low blood pressure in the venous circulation makes the movement of blood against the force of gravity difficult. Blood flow within peripheral veins depends on the contractions of skeletal muscles to propel the blood, and on valves to prevent blood from backing up.
What is the function of venous valves?
Prevent backflow of blood back down the venules and help maintain venous return to the heart
What helps push blood through veins against gravity?
The contraction of adjacent skeletal muscles compresses veins and pushes blood upward
What is an arteriovenous anastomosis?
A vessel that directly connects an artery to a vein, bypassing capillary beds
The pressure of blood within a capillary bed is called
capillary pressure
Capillary exchange between the plasma and interstitial fluid plays a key role in
homeostasis
What is diffusion?
The net movement of ions or molecules from an area where their concentration is higher to an area where there concentration is lower.
What kind of molecules like plasma proteins cannot normally leave the bloodstream?
Larger water-soluble
Lipid-soluble materials-including steriods, fatty acids, and dissolved gases______across the endothelium, passing through the membrane lipids.
diffuse
What is filtration?
the removal of solutes as a solution flows across a porous membrane
Reabsorption takes place as the result of
Osmosis
Osmosis refers to
the diffusion of water across a selectively permeable barrier
Homeostatic processes regulate cardiovascular activity to ensure that tissue blood flow, and meets the demand for oxygen and nutrients also called?
Tissue perfusion
What factors affect tissue blood flow?
Cardiac output, peripheral resistance, and blood pressure
What are the 3 goals of cardiovascular regulation to ensure blow flow changes take place?
At an appropriate time, in the right area, and without drastically altering blood pressure and blood flow to vital organs.
If autoregulation fails to normalize tissue conditions, what is activated as backup?
Neural and endocrine processes are activated
The nervous system responds to changes in
arterial pressure or blood gas levels sensed at specific sites
What nervous system adjusts cardiac output and peripheral resistance to maintain adequate blood flow
Autonomic nervous system
The endocrine system releases hormones that enhance
short-term adjustments and long-term adjustments in cardiovascular performance
Short-term responses adjust
cardiac output and peripheral resistance to stabilize blood pressure and blood flow to tissues
Long-term adjustments involve
alterations in blood volume that affect cardiac output and the transport of oxygen and carbon dioxide to and from active tissues.
Factors that promote the dilation of precapillary sphincters are called
Vasodilators
Those that stimulate the constriction of precapillary sphincters are called
vasoconstrictors