Katzung Chapter 16 Histamine, Serotonin and the Ergot Alkaloids

Dimenhydrinate

First generation antihistamine, used for motion sickness

Diphenhydramine

First generation antihistamine, cold/allergy products and sedative in OTC sleep aid products

Hydroxizine

First generation antihistamine, anti-allergy product with marked sedation

Meclizine

First generation antihistamine, used for motion sickness, less sedation

Promethazine

First generation antihistamine, antiemetic

Chlorpheniramine

First generation antihistamine, cold/allergy products

Fexofenadine

Second generation antihistamine, anti-allergy product (F)

Loratadine

Second generation antihistamine, anti-allergy product (L)

Cetirizine

Second generation antihistamine, anti-allergy product (C)

Sumatriptan

5HT1D/1B receptor agonists used for migraines (S)

Almotriptan

5HT1D/1B receptor agonists used for migraines (A)

Rizatriptan

5HT1D/1B receptor agonists used for migraines (R)

Zolmitriptan

5HT1D/1B receptor agonists used for migraines (Z)

Eletriptan

5HT1D/1B receptor agonists used for migraines (E)

Naratriptan

5HT1D/1B receptor agonists used for migraines (N)

Frovatriptan

5HT1D/1B receptor agonists used for migraines (F)

Melatonin

Food supplement promoted for sleep

Histamine

Mediator of immediate allergic and inflammatory reactions, important role in gastric acid secretions and mediator of immune function (infammation) and chemotaxis od WBCs

Serotonin

Involvedin moodsand diurnal sleep cycles, vasoconstrictor in the brain

Ramelteon

Melatonin agonists for insomnia

Tasimelteon

Melatonin agonists for non 24 hour sleep-wake disorder