Aflatoxicosis
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Last updated 4:57 PM on 11/6/25
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11 Terms
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Which mycotoxin
Aflatoxin
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Toxigenic strain of
Aspergillus
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Contamination
Stored grain and nuts, high moisture
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Which aflatoxin is most potent
Aflatoxin B1
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Where are they absorbed and metabolised
Absorbed in small intestine and metabolised in liver
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What does it bind to
DNA and proteins and inhibit nucleic acid synthesis
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Which type of cell does it mainly damage
Hepatocytes and cause necrosis and fibrosis
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Effects
Carcinogen, mutagenic, teratogenic, immunosuppressive (thymus atrophy)
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Acute findings
Ataxia, tremors, death
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Chronic findings
Poor growth, anorexia, jaundice, hepatophathy
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Liver lesions
Enlarged, pale, fatty degeneration
Note 
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