RBCs: abnormal + inclusions

acanthocyte

Echinocytes are also known as

Burr cells

echinocyte

elliptocyte

macroovalocyte

helmet cells are also known as

keratocyte

RBC fragments are also known as

schistocytes

schistocyte

drepanocytes are also known as

sickle cells

drepanocyte

spherocyte

stomatocytes are also known as

mouth cells

codocytes are also known as

target cells

stomatocyte

codocyte

dacrocytes are also known as

teardrop cells

dacrocytes

stomatocytes are mainly seen in

• hereditary stomatocytosis

• liver disease

stomatocytes can also be seen in

• alcoholism

• Rh null phenotype

drepanocytes are seen in

• Hb SS disease

• hgb SC disease

schistocytes are mainly seen in

• DIC

• hemolytic processes

schistocytes are also seen in

• MAHA

• severe burns

• renal graft rejection

acanthocytes are mainly seen in

• abetalipoproteinemia

• severe liver disease

acanthocytes can also be seen in :

• splenectomy

• malabsorption

• hypothyroidism

• vitamin E deficiency

dacrocytes are mainly seen in

• extramedullary hematopoiesis

• thalassemias

• pernicious anemias

dacrocytes can also be seen in

• myelofibrosis

• megaloblastic anemia

• myelophthisic anemia

spherocytes are mainly seen in

• hereditary spherocytosis

• ABO HDN

• other hemolytic processes

spherocytes can also be seen in

• hemolytic anemias

• transfused cells

• severe burns

elliptocytes are mainly seen in

• hereditary elliptocytosis

• iron deficiency

• thalassemia

macroovalocytes are mainly seen in

megaloblastic anemia

elliptocytes and ovalocytes may be seen in

• iron deficiency anemia

• megaloblastic anemia

• myelophthisic anemia

codocytes are mainly seen in

• liver disease (obstructive)

• Hb C

• thalassemias

• hemoglobinopathies

codocytes may also be seen in

• splenectomy

  • with jaundice

echinocytes are mainly seen in

• uremia

• artifact (alkaline glass effect)

echinocytes may also be seen due to

• pyruvate kinase deficiency

• MAHA

• poor slide prep

• prolonged specimen storage

Howell-Jolly bodies are composed of

DNA

basophilic stippling is composed of

RNA

pappenheimer bodies are composed of

iron

pappenheimer bodies are also known as

siderotic granules

a cell that contains pappenheimer bodies is called a _

siderocyte

heinz bodies are composed of:

denatured precipitated hemoglobin

cabot rings are composed of

remnants of mitotic spindle

what parasites can be seen in red cells

• malaria

• babesia

• trypanosomes

what stains are used to see HJ bodies

• wright

• new methylene blue

w

what stain(s) are used to visualize pappenheimer bodies

wright

what stain(s) are used to confirm pappenheimer bodies

Prussian blue

what stain(s) are used to visualize basophilic stippling

• wright

• new methylene blue

what stain(s) are used to visualize heinz bodies

supravital stain

• brilliant cresyl blue

• new methylene blue

can heinz bodies be seen with the wright stain

NO

which red cell inclusion cannot be seen using the Wright stain

heinz bodies

what stain(s) are used to visualize cabot rings

wright stain

what stain(s) are used to visualize parasites in red cells

wright stain

which red cell inclusions can be seen with the Wright stain

• HJ body

• basophilic stippling

• pappenheimer

• cabot rings

• parasites

which red cell inclusions can be seen with a new methylene blue stain

• HJ body

• basophilic stippling

• heinz body

which red cell inclusion can be seen using prussian blue stain

pappenheimer bodies

pappenheimer bodies are mainly indicative of:

• sideroblastic anemia

• hemoglobinopathies

pappenheimer bodies can also be seen in

• splenectomy

• hemolytic anemia

• megaloblastic anemia

basophilic stippling is mainly indicative of

• lead poisoning

• thalassemia

basophilic stippling may also be seen due to

abnormal heme synthesis

howell-jolly bodies are mainly indicative of

• disturbed erythropoiesis

• hemolytic anemias

• megaloblastic anemia

• post-splenectomy

HJ bodies may also been seen because of

hyposplenism

heinz bodies are mainly indicative of

• G6PD deficiency

• thalassemia

• unstable hemoglobin

cabot rings are indicative of

megaloblastic anemia

acanthocytes are also known as

spur cells