Serotonin Receptor Antagonists -tron
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Description and Tags
Anti-emetics
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5 Terms
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Drugs in class
ondansetron (Zofran)
granistron (Kytril)
dolasetron (Anzemet)
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Properties/MOA
-Acts by blocking serotonin
5HT3 receptors
• Most effective against N/V
caused by chemo
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Effects/Adverse Rxn
HA
Constipation
N/V
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Contraindications
Contraindicated in
patients w/hypersensitivity to drug
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Nursing info
-Zofran can be used as oral
dissolved tablet
• dexamethasone (Decadron)
used to ↑ effectiveness of
drug
Note 
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