AP BIo Genetic Diseases

Autosomal Recessive

Must inherit two mutated genetics to get the trai/disease

Autosomal Dominant

Must inherit one mutated gene to get the trait/disease

Sex-linked recessive

Genetic mutations caused by mutated X chromosomes

• Seen more in males because they only inherit one X

  • Xx = safe, xy = mutated

Sex- linked dominant

A rare disorder when one mutated X chromosomes causes the disorder

• Prevalent in both males and females

Cystic Fibrosis (inheritance)

Autosmal recessive

Cystic Fibrosis (affect)

Causes build up in the lungs

• breathing problems, infections etc

Tay Sachs (inheritance)

Autosomal recessive

Tay Sachs (affect_

Non-functioning enzymes that fail to break down lipids

• Destroys nerve cells

Sickle Cell (inheritance)

Autosomal recessive

Sickle Cell (affect)

Mutation of an amino acid in the hemoglobin

• Affects red blood cells

P.K.U Iinheritance)

Autosomal recessive

P.K.U (affect)

Results in a non existent enzyme, cant brake down phenyalanine hydroxylase (Amino acid)

Huntigtons Disease (Inheritance)

Autosomal Dominant

Huntingtons Disease (affect)

Progressive loss of nerve cells in the brain

Dwarfism (inheritance)

Autosomal Dominant

Aeromegly (inhertance)

Autosomal Dominant

Aeromegly (affect)

Giantism

Hemophilia (inheritance)

Sex - Linked recessive

Hemophilia (affect)

Blood disease

• Uncontrollable bleeding

Red/Green Color Blindness

Sex - linked recessive

Downs syndrome (inheritance)

Autosomal/Aneuploidy

Jacabs (inheritance)

Sex - Chromosome Aneuploidy

• Extra Y (XYY)

Trisomy (inheritance)

Sex-Chromosome Aneuploidy

Kleinfelter (inheritance)

Sex-Chromosome Aneuploidy

Kleinfelter (affect)

Sterile Males (XXY)

Turners (Inheritance)

Sex - Chromosome Aneuploidy

Turners (affect)

When females miss one x (X0)