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4 regions of the brain
cerebrum, diencephalon, brainstem, cerebellum
Cerebrum functions
- performs higher mental functions
- interprets sensory stimuli
- plans & initiates movement
Hypoglossal nerve XII
- motor
- medulla oblongata
- tongue
- swallowing and food manipulation
Accessory Nerve XI
swallowing, head, neck, and shoulder movements (motor)
- medulla oblongata
Vagus Nerve X
sensory: origin: tongue neck & pharynx
destination: medulla oblongata
taste from posterior tongue & hunger sensation
Motor: origin: medulla oblongata
destination most/all vital organs
controls glands and smooth muscle
Glossopharynheal nerve IX
Sensory:
Origin: tongue & pharynx
Destination: cerebrum
Function: taste sensation from remaining 2/3 of the tongue
Motor:
origin: medulla oblongata
Destination: tongue & pharynx
Function: swallowing, salivation and gagging
Vestibulocochlear nerve VIII
Sensory
Origin: choclea within the ear
vestibule of ear
Destination: Cochlear nuclei & vestibular nuclei within medulla oblongata
Function: Hearing, balance and equilibrium
Facial nerve VII
Sensory
Origin: tongue eye palate and nasal cavity
Destination: Primary somatosensory cortex
Function: taste sensation from anterior 2/3 of tongue
Motor:
Origin: Pon
Destination: Facial muscles
Function: facial expression & tear/ salvia secretion
Abducens Nerve VI
Motor
Origin: Pons
Destination: Lateral rectus muscle
Function: lateral eye movements
Trigeminal nerve
sensory
Origin: within receptors of the face
Destination: Primary somatosensory context
Function: tactile sensations from face & head- sneeze reflex
Motor
Origin: pons
Destination: facial muscles
Function: to control chewing
Trochlear nerve IV
Motor
Origin: mesencephalon
Destination: Superior oblique muscle
Function: inferolateral eye movements
Oculomotor nerve III
Motor
Origin: mesencephalon of the brain
Destination: Intrisnic and extrinsic eye muscles
Function: moves eye up/down/medially
- visual accommadation
- opens eye life & pupil constriction
damage : dipolopia
Optic Nerve II
Sensory
Origin:retina of the eye
Destination:diencephalon
Function: Sense of vision
Olfactory nerve
sensory
Origin:originates on the olfactory epithelium
Destination:olfactory bulbs
Function: sense of smell
Damage: causes anosmia (lack of smell)
Shingles
viral disease that affects the peripheral nerves and causes blisters on the skin that follow the course of the affected nerves
Polio
A highly contagious infectious disease of the spinal cord caused by a filterable virus.
Multiple sclerosis
MS- autoimmune disorder inflammation of brain and spinal cord
Paraplegia
paralysis of the lower limbs
Quadriplegia
paralysis of all four limbs
Withdrawl Reflex
avoidance of painful stimuli
ex: touching a hot pan
Stretch reflex
muscle contracts in response to stretch
simplest reflex
Development reflex
Innate: @ birth
Acquired: Develop/change after birth
Response reflex
Somatic : contraction/relaxation of skeletal muscles
Autonomic: involves cardia muscle, smooth muscle or glands
Processing site reflex
Cranial : processed in the brain
Spinal: processed in spinal cord
Ipsilateral / contralateral reflex
Ips: receptor & effector on the same side of the body
Contr: receptor & effector on opposite sides of the body
Number of synapses
Monosynaptic: direct communication of sensory& motor neurons
Polysynaptic: interneurons present
Sacral plexus nerve
L4-S4
Sciatic nerve
Lumbar plexus
L1-L4
innervates anterloateral body wall, genitalia, parts of lower limb
Brachial plexus
C5-T1
ulnar nerve & median nerve
Cervical plexus
C1-C5
*phrenic nerve: innervates the diaphragm - breathing_
Peripheral neuropathies
regional losses of sensory and motor function most often resulting from nerve trauma or compression
Dermatome
Area of skin supplied by a single spinal nerve
Dorsal ramus
sensory & motor information to and from the back
Ventral ramus
sensory & motor information to and from the limbs
Ventral rami: merge to form the nerve plexuses
Gray ramus
carries unmyelinated postganglionic neurons
white ramus
carries myelinated preganglion neurons
Epineurium
surrounds the entire nerve
Perineurium
surrounds each fascicle
Endoneurium
surrounds the axons
Ventral root
motor
Dorsal root
sensory
Dorsal root ganglion
forms spinal nerve
unipolar neurons
Nerve tracts
Fasciculus
Ascending nerve tracts
Contains sensory information
Descending nerve tracts
Contains motor information
Anterior white commissure
site of crossing over axons
Anterior median fissure
wider groove on the anterior surface
Posterior median sulcus
Narrow groove on posterior surface
Posterior gray commissure
Sites of neuron/ axons crossing over
Central canal
contains the cerebral spinal fluid
Conus medullaris
tapered end of the spinal cord (L1-L2)
Cauda equina
collection of spinal nerves below the end of the spinal cord
Filum terminale
anchors spinal cord to coccyx
Cervical enlargement
where nerves supply upper limbs and enter+exit the spinal cord
Lumbar enlargement
nerves of pelvis and lower limbs
Epidural
injecting anesthesis into epidural space
Lumbar puncture
Inserting a needle into subrachnoid space
- below spinal cord so no risk of hitting the cord
- pulls out spinal fluid
- Checks for meningitis
Epidural space
space between the dura mater and the wall of the vertebral canal
Subdural space
space between dura mater and arachnoid mater
Subarachnoid space
arachnoid & pia mater contains CSF
Dura mater
Single layer
Arachnoid Mater
middle layer of the meninges
Pia mater
Bound to spinal cord surface
helps anchor spinal cord in place
Functions of CSF
buoyancy, protection, chemical stability
Choroid plexus
A highly vascular portion of the lining of the ventricles that secretes cerebrospinal fluid.
80% made in the lateral ventricles
3rd ventricle
diencephalon
Cerebral aqueduct
connects 3rd and 4th ventricles
4th ventricle
begins in the mesencephalon extends into medulla oblongata and becomes the central canal of spinal cord
Lateral ventricles
A set of paired ventricles lying within the cerebral hemispheres.
Interventricular foramen
connects lateral ventricles to third ventricle
Arachnoid mater
Thin & delicate layer
Arachnoid granulations
collections of arachnoid villi
returns CSF back into the blood
Pia mater
thin, delicate inner membrane of the meninges
bound by astrocytes
Subdural space
between the dura and arachnoid mater
subdural hematoma occurs here
what do the dural folds do?
stabilize and support the brain
Falax cerebri
separates cerebral hemispheres
Falx Cerebelli
separates the two hemispheres of the cerebellum
Tentorium cerebelli
separates cerebellum from cerebrum
Dura mater
TOugh leather layer and has 2 portions
Periosteal layer
fuse to the periosteum of skull
highly vascular
Meningeal layer
Inner layer
continuous with the dura mater of spinal cord
Avascular
Blood brain barrier
A mechanism that prevents certain molecule from entering the brain but allows others to cross
ASTROCYTES wrap around capillaries of the brain
water soluble yes can pass
Alpha waves
Healthy awake adults
Change to another wave when you fall asleep or start to concentrat
Beta waves
Seen when concentrating or during stress
normal wakening brain wave
Theta waves
common in kids
seen in adults when frusterated
Delta waves
common when sleeping at all ages
Cerebellar functions
1. Vestibulocerebellum
2. spinocerebellum
3. Cerebrocerebellum
Vestibulocerebellum
maintains muscle tone and postural muscles
Spinocerebellum
Enhances muscle tone and coordinates skilled, voluntary movements
Cerebrocerebellum
motor planning
Cerebellum
communicates with other regions of the CNS via cerebellar peduncles
Superior cerebellar peduncles
Connects mesencephalon, diencephalon and cerebrum
Middle cerebellar peduncles
Connects to pons
Inferior cerebellar peduncles
connect medulla oblongata and spinal cord
Arbor vitae
white mater in cerebellum
folia
folds in the cerebellum
Vermis
Seperates 2 hemispheres of cerebellum
Purkinje cells
Largest cells in cns
within the coretex of cerebellum
mainly acts as inhibiotry neuron
Anterior nucleus (hypo)
contains thirst centers
Arcuate nucleus
regulate appetite by controlling hunger sensations
produces hormones of the anterior pituitary gland