5.5 Insomnia Therapeutics

Nickelson

T/F sleep hygiene is enough for sole intervention of insomnia

F

insomnia tx with hynoptics:

use ___ term and at ___ doses

short

low

diphenhydramine class

hypnotic antihistamine

doxylamine class

hypnotic antihistamine

short term primary insomnia hypnotics of choice

benzos or z-drugs

flurazepam class

hypnotic benzo

temazepam class

hypnotic benzo

triazolam class

hypnotic benzo

triazolam is ____ acting

ultra short

Quazepam class

hypnotic benzo

Estazolam class

hypnotic benzo

zolpidem class

BZD1 receptor agonist (z-drug)

zaleplon class

BZD1 receptor agonist (z-drug)

eszoclipone class

BZD1 receptor agonist (z-drug)

which drugs induce the FASTEST onset of sleep?

temazepam

zolpidem

which drugs induce the slowest onset of sleep?

flurazepam

estazolam

which drugs increase the total sleep time?

flurazepam

temazepam

estazolam

which drug induces the lowest total sleep time?

zolpidem

ramelteon class

selective melatonin receptor agonist

which agent is pref for old ppl

ramelteon

suvorexant class

orexin receptor antagonist

lemborexant class

orexin antagonist

daridorexant class

orexin antagonist

trazodone class

serotonin antagonist and reuptake inhibitors (SARIs)

atypical antidepressant

gabapentin class

anticonvulsant / antiepileptic

tiagabine classs

anticonvulsant / antiepileptic

quetiapine class

atypical antipsychotic

short acting agents should be used for pts who need help with..

falling asleep (sleep onset/ latency)

_______ acting mediations should be used for pts who need help falling asleep (sleep latency)

short

lorazepam class

hypnotic benzo

sleep maintenance insomnia requires _____ acting agents

long

T/F

long term treatment of insomnia with meds is chill

F

select medications based on…

kinetics

comorbidities

CI and precautions

benzo warnings/ADE

withdrawal and dependence

z-drug warnings

huge risk for doing activities while asleep (driving, cooking, walking, etc, things that could kill you)

special pop tx for insomnia

treat underlying conditions before treating insomnia

elderly pts can have ramelteon

pediatrics should not take ramelteon

pts with drug abuse hx can take ramelteon

which drugs are indicated for sleep latency

zolpidem

zaleplon

triazolam

lorazepam

ramelteon

which drugs are indicated for sleep maintenance

zolpidem ER

ezsciplone

temazepam

estazolam

suvorexant