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The glomerulus is primarily responsible for ____ of unbound drug in the kidney.
a. Filtration
b. Reabsorption
c. Secretion
d. Endocytosis
a. Filtration
Active drug secretion occurs most often in which of the following nephron segments?
a. Glomerulus
b. Proximal tubule
c. Loop of Henle
d. Distal tubule
b. Proximal tubule
According to the intact nephron hypothesis, single nephron GFR _____ in the surviving nephrons.
a. Decreases
b. Increases
c. Remains the same
b. Increases
The kidney is responsible for synthesizing each of the following hormones, except:
a. Erythropoietin
b. Prostaglandin
c. PTH
d. Renin
c. PTH
Which of the following kidney function indices is least affected by dietary protein intake?
a. Serum creatinine
b. Blood urea nitrogen (BUN)
c. Creatinine clearance
d. Urine sodium
d. Urine sodium