Heme Peripheral Smears

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9 Terms

1
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<p><span>Schistocytes</span></p>

Schistocytes

  • Fragmented helmet** shaped cells, or pieces of RBCs

  • May indicate a LIFE THREATENING PROCESS

  • destruction, hemolytic anemia

2
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<p><span>Ovalocyte</span></p>

Ovalocyte

  • Egg like or oval shaped cell

  • B12/folic acid deficiency (diet) if macrocytic

3
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<p><span>Dacrocyte</span></p>

Dacrocyte

  • Teardrop or pear-shaped with a single elongated point or tail

  • cancer (myelofibrosis), thalassemia

4
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<p><br><span>Target cells</span></p>


Target cells

  • Bull's-eye appearance

  • Iron-deficiency anemia**, thalassemia

5
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<p><span>Spherocytes</span></p>

Spherocytes

  • Condensed and absence of central pallor

  • Hereditary spherocytosis, immune or autoimmune hemolytic anemia

6
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<p><span>Basophilic Stippling</span></p>

Basophilic Stippling

  • Dust-like to coarse, round granules

  • thalassemia**, lead or heavy metal poisoning

7
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<p><span>Heinz Bodies</span></p>

Heinz Bodies

  • Bite cells are evidence that Heinz body has been removed by the spleen

  • G6PD deficiency***, drug induced anemia

8
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<p><span>Howell-Jolly Bodies</span></p>

Howell-Jolly Bodies

  • Single or double, round, blue inclusions near periphery of RBC

  • Hemolytic anemia***, megaloblastic anemia, hyposplenia, or asplenia

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<p><span>Blister cell</span></p>

Blister cell

  • Clearing or vacuole on one side

  • Hemolytic episodes, G6PD deficiency