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Negative feedback
The response counteracts or reverses the initial change to bring the body back to equilibrium.
Goal of Negative feedback
Stability — to keep conditions within a normal range (set point).
Example of Negative feedback
Body Temperature Regulation:
Stimulus: Body temperature rises.
Receptors: Skin and hypothalamus detect change.
Control Center: Hypothalamus triggers response.
Effectors: Sweat glands activate → body cools → temperature returns to normal.
Homeostasis
the process by which the body maintains a stable internal environment despite external changes (e.g., maintaining body temperature, blood sugar, or pH).
Positive feedback
The response amplifies or enhances the original stimulus.
Goal of positive feedback
Drives a process to completion rather than maintaining balance.
Exampel of postive feedback
Childbirth: Stretching of the uterus triggers oxytocin release, which increases contractions — leading to more stretching until the baby is delivered.
Stimulus
The change in environment that disrupts balance
Example of Stimulus
Heat increases body temperature
Receptor (sensor)
Detects the change and sends information to the control center
Example of receptor
Skin nerve endings detect heat
Control Center
Processes the information and determines the proper response
Example of Control Center
Hypothalamus in the brain
Effector
Carries out the command from the control center
Example of Effector
Sweat glands, blood vessels
Response
The result that restores balance
Example of Response
Sweating and vasodilation lower temperature
Main function of Epithelial tissues
Protection, absorption, secretion, filtration
Location of Epithelial Tissues
Covers body surfaces, lines organs, forms glands
Characteristics of Epithelial tissues
Closely packed cells with minimal matrix; avascular (no blood supply); regenerate quickly
Main Function of Connective tissues
Support, binding, protection, transport
Location Connective Tissues
Found everywhere (bone, fat, blood)
Charcteristics of Connective Tissues
Cells scattered within a non-living extracellular matrix
Function of Muscle
Movement (internal and external)
Location of Muscle Tissue
Skeletal muscles, heart, walls of organs
Charcteristcs of Muscle Tissue
Contractile tissue; elongated cells with actin and myosin filaments
Function of Nervous Tissues
Communication and control
Location of Nervous Tissues
Brain, spinal cord, nerves
Characteristics of Nervous Tissue
Neurons transmit signals; neuroglia support neurons
Simple
one layer (for absorption, secretion, diffusion)
Stratified
multiple layers (for protection)
Pseudostratified
looks multilayered but is one layer with nuclei at different levels
Squamous
flat, thin cells (for diffusion)
Cuboidal
cube-like cells (for secretion/absorption)
Columnar
tall, rectangular cells (for absorption/secretion)
Structure of Simple Squamous
Single, thin layer of flat cells
Location of SImple Squamous
Lungs (alveoli), capillaries
Function of Simple Squamous
Allows diffusion and filtration
Structure of Simple Cuboidal
Single layer of cube-shaped cells
Location of Simple Cuboidal
Kidney tubules, glands
Function of Simple Cuboidal
Secretion and absorption
Structure of Simple Columnar
Single layer of tall cells (may have microvilli/goblet cells)
Location of Simple Columnar
Digestive tract lining
Function of Simple Columnar
Absorption and mucus secretion
Structure of Pseudostratified Columnar
Appears layered but is not; often ciliated
Location of Pseudostratified Columnar
Trachea, respiratory tract
Function of Pseudostratified Columnar
Moves mucus; protects airways
Structure of Stratified Squamous
Many layers; outer cells flat and dead (keratinized)
Location of Stratified Squamous
Skin, mouth, esophagus
Function of Stratified Squamous
Protection from abrasion
Structure of Transitional Epithelium
Layers of rounded cells that stretch
Location of Transitional Epithelium
Urinary bladder
Function of Transitional Epithelium
Stretching and recoil for urine storage
Cilia
Hair-like extensions that move substances along surfaces (e.g., move mucus in respiratory tract).
Microvilli
Finger-like projections that increase surface area for absorption (e.g., intestines)
Goblet Cells
Specialized epithelial cells that secrete mucus to protect and lubricate.
Apical Surface
Exposed to the body’s exterior or to an open space inside an organ (lumen).
Basal Surface
Attached to the basement membrane; anchors cells to connective tissue.
Basement Membrane
A thin layer of proteins and fibers that connects epithelial tissue to underlying connective tissue and provides structural support.
Exocrine Glands
Have ducts that secrete substances onto surfaces or into cavities.
Examples: Sweat glands, salivary glands, oil glands.
Endocrine Glands
Ductless glands that secrete hormones directly into the bloodstream.
Examples: Thyroid, pancreas (insulin production).
Cells in Connective Tissue
Specialized cells like fibroblasts, chondrocytes, osteocytes, blood cells
Function of Cells in Connective Tissues
Create and maintain matrix
Collagen Fibers in Connective Tissues
Thick, strong, non-elastic fibers
Function of Collagen Fibers in Connective Tissues
Provide tensile strength
Elastic Fibers in Connective Tissues
Thin, stretchy fibers made of elastin
Function fo Elastic Fibers in Connective Tissues
Provide flexibility and resilience
Reticular Fibers in Connective Tissues
Fine, branching collagen fibers
Function of Reticular Fibers in Connective Fibers
Form supportive frameworks
Ground Substance in Connective Tissues
Gel-like material filling space between fibers
Function of Ground Substance
Supports cells, stores nutrients, allows diffusion
Areolar Function
Cushions organs, holds tissues together
Areolar Structure
Loose fibers, open space
Location of Areolar
Beneath epithelium, around blood vessels
Adipose Function
Stores fat, insulates, protects
Adipose Structure
Densely packed fat cells
Location of Adipose
Under skin, around kidneys, heart
Dense Regular Function
Resists tension in one direction
Dense Regular Structure
Collagen fibers arranged in parallel
Dense Regular Location
Tendons, ligaments
Hyaline Cartilage Function
Smooth surface for movement
Hyaline Cartilage Structure
Glassy matrix with chondrocytes
Hyaline Cartilage Location
Ends of bones, trachea, nose
Bone (Osseous) Function
Structure, protection, mineral storage
Bone (Osseous) Structure
Rigid matrix with calcium and collagen
Bone (Osseous) Location
Skeleton
Blood Function
Transports oxygen, nutrients, waste
Blood Structure
Plasma matrix with red and white cells
Blood Location
Within blood vessels
Tendons
Connect muscle to bone
Ligaments
Connect bone to bone.
Ligaments and tendons are made up of
Dense regular connective tissue — packed with strong collagen fibers arranged in parallel for strength
Hyaline Cartilage Location
Nose, trachea, ends of long bones
Hyaline Cartilage Function
Flexibility and smooth surface
Hyaline Cartilage Special Trait
Glassy appearance
Elastic Cartilage Location
Ear, epiglottis
Elastic Cartilage Function
Flexibility with shape retention
Elastic Cartilage Special Trait
Contains elastic fibers
Fibrocartilage Location
Intervertebral discs, pubic symphysis
Fibrocartilage Function
Absorbs Shock