3) Pathophysiology of glomerular disease and nephritic syndrome

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10 Terms

1
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Why is the glomerular capillary wall especially vulnerable to immune-mediated injury?

It is highly vascular, under high pressure, and has a negatively charged filtration surface that attracts immune complexes

2
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Is goodpasture syndrome endogenous or exogenous

Endogenous

3
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Which of the following is a typical gross finding in chronic glomerulonephritis?

Small, shrunken kidneys with a granular cortical surface

4
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Which of the following best describes the glomerular histology in chronic glomerulonephritis?

Global glomerulosclerosis with obliteration of capillary loops

5
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What tubular or interstitial changes are commonly seen in chronic glomerulonephritis?

Tubular atrophy, interstitial fibrosis, and lymphocytic infiltration

6
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Which of the following best represents the five main pathological effects of glomerular disease?

Proteinuria, hematuria, reduced GFR, hypertension, and edema

7
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Which of the following list correctly identifies the major causes of nephritic syndrome?

IgA nephropathy, post-infectious glomerulonephritis, lupus nephritis, membranoproliferative GN, rapidly progressive GN, Alport syndrome, wegeners syndrome, and Henoch-Schönlein purpura

8
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<p>What is this</p>

What is this

Post infective glomerulonephritis

9
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<p>what is this</p>

what is this

RPGN

10
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<p>What is this</p>

What is this

IgA nephropathy