Aplastic Anemia Overview

These flashcards cover the key concepts related to aplastic anemia, including definitions, causes, and pathophysiological mechanisms.

Aplastic Anemia

A condition characterized by reduced growth or production of blood cells.

Hypoproliferative Disorders

A group of disorders that include aplastic anemia, characterized by reduced growth or production of blood cells.

Idiopathic Aplastic Anemia

A form of aplastic anemia with no known cause.

Iatrogenic Agents

Agents that cause diseases as a result of medical treatment, including benzene and antibiotics.

Immune-Mediated Causes

Causes of aplastic anemia that involve the immune system, such as transfusion-associated graft versus host disease.

Cytotoxic T Cells

A type of immune cell that can cause damage in aplastic anemia by attacking hematopoietic cells.

Hematopoietic Failure Pathophysiology

A process involving insufficient or defective stem cells leading to failure in blood cell production.

Telomere Repair Gene Mutations

Mutations that can impair the function of stem cells in aplastic anemia.

Eosinophilic Fasciitis

An immune-mediated disorder that can be classified as a cause of aplastic anemia.

Parvovirus Infection

A viral infection that may cause transient immune suppression related to aplastic anemia.