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What are 2 difference with light microscopy?
- Shorter wave length = high resolution
- Uses e- instead of light photons
How are electrons used? (2)
- e- beams are focused by electromagnetic lenses in vacuum
- e- passes specimen and gets excited so emits light
Magnification ratio?
1000 - 250,000
How is an image made?
- Due to bouncing off excited electrons = emits light
Why does specimen need to be fixed and stained with HEAVY METALS? (2)
- Cells have LOW ATOMIC NUMBER so SCATTERING is poor
- Increase density = Increase contrast