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AFP
Alpha Fetoprotein
abnormal levels may indicate a neural tube defect or development problem - Amniotic fluid will be used to confirm results
Antisepsis
process of using antiseptics to eliminate microorganisms that cause disease
arrhythmia
abnormal rate of heart muscle contractions
asepsis
the state of being free from disease causeing organisms/pathogens by preventing contact with them
autologous blood transfusion
intraoperative blood salvage, pt receives own blood - autotransfusion
battery
the unpriviledged touching of a person by another,
intentional touching of a patient without permission is battery
bleeding time
test to ascertain PLT function, cut the pt special paper to wipe away blood and see how long it takes for plts to form a plug
bloodborne infection
infection transmitted blood to blood
thrombus
clot that forms inside a blood vessel
emobolus
a clot that moves inside a vessel
Cavicide
intermediate level surface disenfectant effective against -
TB, HIV, HBV, HCV, viruses, bacteria (MRE and VRE), and fungus
Chain of Custody can apply to what kinds of tests?
drug, paternity, DNA, DUI/Blood Etoh, forensic studies,
citrate
a compound intermediate in the Krebs cycle
Citrate binds to calcium ions preventing clotting = anticoag
CLIA
clinical laboratory improvement ammendents of 1988
fed reg standards that apply to all clinical lab testing on humans in US (Except clinical trials and research)
CLIA requirements for waived testing
-if they are simple tests with an insignif risk of an erroneous result
-already ok’ed by FDA for home use
coagulation factors
a group of plasma proteins (factors 1 - 13) that act together to bring about coagulation
CBC
complete blood count
# of RBC, WBC’s and PLTs present per cubic ML
plus H&H, and diff
Coumadin
tradename for warfarin, blood thinner
Creatine clearance
24hr hr urine and serum test for both blood and urine collection
pt voids at 8am, discards specimen, then collects all urine until 8am the next morning, along with a blood draw the final morning
CRP
c reactive protein - marker for inflammation that is made in the liver
drawn in SST or Lavender
cystitis
bladder infection or inflammation
D-Dimer
light blue tube
rules out presense of a clot (DVT or PE)
Defamation of character
intentional injury to another person’s reputation, name or character through spoken (slander) or written (libel) words
diurnal variation testing
measuring of a body’s ability to metabolize substances over time (24 hrs)
DNR
do not resuscitate, a patient with a DNR should not have a code called or any heroic measures
Electrolyte
a substance that will acquire the ability to conduct electricity when put into solutionWh
what chemicals are Lytes
sodium
K
chloride
calcium
phosphate
What are examples of emobli?
detached clot
bacterial clump
foreign material (air thrombus)
EMLA
eutectic mixture of local anesthestic
topical spray or cream that numbs the site before puncture
Endocrine system
regulates body activies through hormones that influence growth, development, and metabolic activities
maintains homeostasis
How do you convert Farenheit into Celsius?
C = (F-32) x 5/9
How do you convert Celsius into Farenheit ?
F = (C X 9/5) + 32
fibrin
protein formed during blood clotting, the essence of the clot
Fibrinogen
the protein from which fibrin is formed
fibrin strands
forms in centrifuged blood when the blood was not allowed to clot for 30 mins before spinning
fomite
an inanimate object that transports microorganisms
Formed elements
RBC’s
WBC’s
PLT
Galactosemia
rare genetic metabolic disorder that affects how a person metabolizes galactose
good samaritan law
law deals with rendering of first aid by healthcare professionals at an accident or if sudden injury, encourages providers to provide medical care without the fear of being sued for negligence
GH
growth hromone - stimulates AA’s used for protein synthesis, causes lipolysis to catabolize fatty acids,
Can be used to stimulate muscle and break down fat
Urea Breath Test
test for H pylorihe
hematocrit
tests for total red blood cell volyme ratio (percentage)
Hemochron signature Elite
POCT device used to check PT/INR
Hemoconcentration
decrease in blood fluid (plasma) which increase concentration
caused by filtration of plasma into body tissue or dehydration
hemoglobinuria
excretion of hemoglobin in urine
hemolytic anemia
reduction in red cells due to excessive destruction in the body
-where RBC’s are being destroyed and removed from blood stream before their normal lifespan is over
hemostasis
the arrest of bleeding from
normal vasoconstriction
surgical ligation
or abnormal obstruction (plaque)
heparin
anticoagulant that inhibits several coag factors, but esp. Factor Xa
Where is heparin formed
forms in our liver
what are the three types of heparin
ammonium heparin - in capillary tubes
in vacutainer tubes:
sodium heparin
lithium heparin
Hepatitis D
usually acquired with Hep B - coinfection or superinfection
bloodborne or mother to babyduring birth
what is iatrogenic anemia
anemia (decrease in RBC’s or HB) caused by repeated blood draws
how do you prevent iatrogenic anemia
blood conservation
don’t draw unnecessary samples
draw minimum amount /Volume
reducing sampling frequency
Use smaller blood volume containers
What percentage of blood removal can be life threatening?
10%
Who is most at risk for iatrogenic anemia?
pediatrics and geriatrics
What is the max percentage of blood volume that can be drawn in an infant?
10ML’s
What is the max blood bolume you can draw in an adult?
100ML
How do you calculate how much volume you can draw to avoid iatrogenic anemia in infants?
Convert wt to kilograms
Wt in Kilos x 100 to get volume in ML’s
Figure out what is 10% of the total bv - to get max amount
document amount of blood collected in each tube
Idiopathic anemia
type of anemia where the patient’s bone marrow stops making new RBC’s
indirect infection
infection that is transmitted through body fluids to blood
informed consent includes explaining what to the patient about a procedure
method
risks
consquences
expective outcomes
alternatives
Inoculate
to implant a disease agent or antigen in a person
invasion of privacy
releasing medical records without patient prior knowledge or permission
layperson terms
using words a person who is not an expert can understand
LIS
laboratory information system
used to order tests, print labels for specimens, and enter results
Liter
primary metric unit of volume
Meter
primary metric unit of distance
Multi-sample adapter
a device that is used with a butterfly or vacutainer holder allowing for the withdrawal of multiple blood tubes
N95 Respirator Mask
respiratory PPE that has a close facia fit and filters out 95% of airborne particles (0.3 microns) -
Required with TB patients
NCCLS
National Center for Clinical Lab. Standards
national org agency that estab standards for Phlebs.
Negligence
failure to exercise the standard of care that a reasonable person would give under similiar circumstance
The 4 elements of neglience are
Duty of Care
Derelict - breach of duty of care
Direct Cause - legally recognized injury occurs as a result of #2
Damage - the wrongful activity must have caused injury or harm
neonate
newborn - especially the human infant during the 1st month after birth
Noscomial infection
infections aquired in a healthcare settings
pernicious anemia
when RBC’s lack the ability to absorb B12
Peripheral Blood
Blood obtained at a distance from the heart (fingertip, heel, earlobe or AC vein)
phlebitis
inflammation of a vein as result of repeated venipuncture
platelet
aka thrombocyte, 2-4 microns in diameter
no nucleus or DNA
formed by breaking off from the parent cell cytoplasm (megakaryocyte in bone marrow)
Quality Assurance
assures quality pt care by tracking outcomes through scheduled audits
(appropriability, applicability, and timliness of pt care)
QC
Quality Control - steps or procedures used to check for quality assurance (expiration dates, monitoring glucose monitors, log sheets of fridge temps, calibrating instruments)
QC Testing
making sure equipment performs as expected and alerts the user when problems occur
-help prevent operator error, reagent or test kid deteroriation, instrument malfuction, improper environmental conditions
RAST
radioallergosorbent Test
test used to detect allergies like for peanuts
RBC;s
no nucleus
has hemoglobin
biconcave disc s
septicemia
systemic infection associated with pathogenic oragnisms introduced during venipuncture
Serum
clear portion of the blood that separates after clotting has taken place
thrombophlebitis
inflammation of the vein with a formation of a clot
TORT
an injury or wrong committed with or without force to another person or proerty for which civil liability may be enforced
Examples of tumor marker
AKA Biomarkers
CA - 125 (ovarian ca)
CA 15-3 (breast ca)
CEA (ovarian, breast, lung, pancreas and GI)
PSA - Prostate CA
VAD
vascular access device
any device used to gain access to a vein or artery such as a needle, IV cathether, central line, PICC
whole blood
blood from which none of the elements have been removed
Universal Precautions
prevention strategy in which all blood and potentially infectious materials are treated as infectious regardless of source or a patient’s status
Verbal consent
when a person reads a verbal version of a consent form and they give their verbal consent in place of a written consent to participate
White Cell Count
number of whb’s found in peripheral blood and measured per cubic milliter