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Describe how the endomembrane system works.
- In the nucleus, MRNA copies a gene from a DNA molecule that codes for a protein.
- That copy is transported to the RER via a nuclear pore.
- The ribosomes on the RER are the sites for protein synthesis and so the MRNA gets made into a protein.
- The protein then buds off of the RER and gets packaged into a transport vesicle where it's taken to the Golgi apparatus.
- The transport vesicle fuses with the Golgi apparatus and within, the protein gets modified into a useful shape.
- Then the protein buds off once again, packaged into a secretory vesicle where it's transported to its final destination.
Give examples of a protein’s final destination.
- The secretory vesicle can fuse with the cell membrane and be secreted to be used outside the cell which is exocytosis.
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