Solute reabsorption

What are the two methods of reabsorption utilized within the kidney’s

• transcellular

• paracellular

On the basolateral side in all segments of the nephron exists what pump

Sodium potassium pump

The sodium potassium pump brings ________ in and ________ out

• 2 potassium(k) in

• 3 sodium(na) out

The sodium potassium pump creates a _____ deficit in the cell

sodium

What electrolytes are almost entirely reabsorbed through the nephron

• sodium

• chloride

It is common to see _______ movement alongside Sodium movement

water

What is reabsorbed in the proximal tubules

• sodium

• glucose

• water

• phosphorus

• chloride

• amino acid

• bicarbonate

• calcium

glucose reabsorption is carried out by a carrier making it possible to _______ the process

saturate

When all carrier molecules are working at maximum capacity you have reached the _________

transport maximum

When low levels of a substance appear in the urine before the transport maximum has been reached you’ve reached the ________

transport threshold

When traveling down the loop of Henle the filtrate becomes more ________

concentrated

When traveling up the loop of Henle the filtrate becomes more ________

dilute

The ascending loop of Henle contributes to reabsorption of what molecules

• sodium

• chloride

• potassium

How does the ascending loop of henle aid in the reabsorption of sodium, potassium, and chloride

Through the NaK2Cl pump

The late distal tubules contain ______ cells which are responsive to aldosterone

principal

Principle cells ________ sodium and _________ potassium under the influence of aldosterone

• reabsorb

• secrete

principal cells are the main cells of the _________ and ___________

• distal tubule

• collecting tubule

in the distal tubules exist a cell that regulates PH of filtrate what is its name?

interclated cell

Intercalated cell____ secretes H+ and intercalated cell ____ secretes bicarbonate

• A

• b

The ________ are a transition zone between the distal tubule and collecting duct

connecting tubules

The collecting ducts contain what type of cells

• principal cells

• intercalated cells

What are barrier preventing reabsorption or secretion of molecules

• tight junctions

• adherens junctions

• focal adhesion molecules

______ prevents paracellular transport of molecules

tight junctions

In animals potassium intake must equate to potassium ________

excretion

Potassium excretion is mostly modulated by the ______ and _______ sections of the nephron

• distal tubule

• cortical collecting tubule

under the influence of _______ potassium excretion is increased in the distal tubules

aldosterone

In regards to potassium excretion if flow is slow than is more or less potassium excreted

less

In regards to potassium excretion if flow is fast than is more or less potassium excreted

more

parathyroid hormone increases _________ reabsorption in the kidney

calcium

calcium is reabsorbed in the proximal tubule through _________ means

paracellular

True or false: calcium reabsorption in the proximal tubule is PTH dependent

False

in the ascending loop of henle calcium is reabsorbed via what two methods

• paracellular

• transcellular

In the distal tubule most of calcium reabsorption is done through _____ transport

active

What is the primary site of phosphorus reabsorption

proximal tubule

Use of PTH hormone decreases reabsorption of what molecule

phosphorus

When increasing dietary phosphorus will you see more or less in the urine

more

Phosphorus reabsorption is __________ mediated and therefore is __________

• carrier

• rate limiting

Para thyroid hromone increases the number of __________

sodium calcium countertransporters

In addition to counter transporters calcium also has a __________

basolateral pump

PTH has more impact on calcium reabsorption in the 

distal tubule

If the Integrins are disrupted, what will happen?

Cells detach from basement membrane

You find glucosuria in a cat who is currently normoglycemic. What will you do?​ Check all that are correct.

• recheck urine glucose

• evaluate BUN and creatinine