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What is a cell?
the structural unit of all living things
Name the three basic points of cell theory.
1. A cell is the basic structural and functional unit of living organisms.
2. All organisms are made of cells.
3. All existing cells are produced by other living cells.
In a cell, properties and features of life are _______________.
evident
What is the difference between prokaryotic and eukaryotic cells?
prokaryotic cells don't have membrane-bound organelles and eukaryotic cells do
Where is the DNA of both a prokaryotic cell and a eukaryotic cell found? Why is it different?
in the cytoplasm of a prokaryotic cell and in the nucleus of an eukaryotic cell; the nucleus is a membrane-bound organelle and prokaryotic cells don't have those
What are the main parts of eukaryotic cells?
cell membrane, cytoplasm, nucleus, intracellular fluid
What is the cytoplasm of a eukaryotic cell?
where organelles are suspended
What is the intracellular fluid of a eukaryotic cell?
water, also called cytosol
What is another name for the cell membrane?
plasma membrane
What is the model of the plasma membrane called?
fluid mosaic model
The plasma membrane is a sea of ___________________ in which ___________________ float like icebergs.
lipids; proteins
What are the two main components of the cell membrane?
half lipids and half proteins
What three lipids are a part of the cell membrane?
phospholipids, glycolipids, and cholesterol
What percentage of the lipids in the cell membrane are phospholipids?
75
The phospholipids in the cell membrane arrange themselves in a ____________________ ___________________ when they are part of it.
phospholipid bilayer
What percentage of the lipids in the cell membrane are glycolipids?
5
Glycolipids are part ______________ and part ________________.
lipid and sugar
Glycolipids are only found sticking out of the cell, or on the side with _________________________ fluid.
extracellular
What percentage of the lipids in the cell membrane are cholesterol (a steroid)?
20
In the cell membrane, cholesterol is found where, and why?
tucked in with nonpolar tails; because it is nonpolar and therefore hydrophobic
What is the lipid bilayer of the cell membrane?
two back-to-back layers of three types of lipid molecules
_________________ and _____________________ scattered among a double row of ______________________.
glycolipids and cholesterol; phospholipids
What is an integral protein?
a protein packed tightly with the membrane; parts with heads and parts with tails of phospholipids; embedded in the membrane
What is a peripheral protein?
loosely associated with the membrane; only with the heads of phospholipids
What is an integral transmembrane protein?
integral and on both sides of the membrane
What is glycocalyx?
sugar coating on outside of cell; made from sugars of glycoproteins and glycolipids
What is glycocalyx used for?
cell identification
Glycocalyx is __________________ in every organism's cells.
different
What are the functions of membrane proteins?
formation of channel, transportation, reception, cell identification, linking, act as enzymes
What is the top of a cell called?
apical surface
What is the bottom of a cell called?
basal surface
What are the three membrane junctions?
microvilli, cilia, flagellum
What is the purpose of microvilli?
absorption
What is the purpose of cilia?
movement of material over the apical surface of the cell
What is the purpose of a flagellum?
movement of the cell
What do microvilli do?
absorb nutrients
What stand microvilli up?
actin proteins
What do microvilli look like?
fingers
What are microvilli covered by?
plasma membrane
We have ___________________ to absorb more nutrients from _____________________; they also ___________________ surface area of the ______________________________________.
microvilli; intestines; increase; plasma membrane
What make up cilia?
proteins called microtubules covered in plasma membrane
Cilia are _________________ than microvilli.
longer
What make up a flagellum?
microtubules covered in plasma membrane
How does a flagellum work?
when microtubules bend, whip-like flagellum propels the cell forward
Where are special membrane junctions found?
in animals
What hold cells together in tissues?
glycocalyx and special membrane junctions
What are the three special membrane junctions?
tight junctions, gap junctions, desmosomes
What is a tight junction?
storage junction inside of the bladder that holds cells together in a tissue
What is one place where a tight junction is used?
to keep urine inside the bladder instead of leaking into the body cavity
How do tight junctions work?
protruding membrane proteins meet with each other and seal intercellular space or space between cells (seal two cells together)
What is a gap junction?
a communication junction that allows ions to flow from cell to cell and allows for synchronized contraction of muscles
How do gap junctions work?
membrane proteins from both cells form passageways from one cell to another; made from proteins called connexxon proteins
What is a desmosome?
a junction that helps dissipate the pressure by spreading it across the cells; keep cells from splitting with button-like adhesion
Where are desmosomes typically found?
in places with a lot of mechanical pressure
How do desmosomes work?
protein plaques in each cell send out cadherin proteins to bond cells, intermediate filaments attach
What are the two types of transport across the plasma membrane? What is the difference?
passive transport does not use energy and active transport uses energy to transport material (ATP)
What are the two types/categories of passive transport?
diffusion and filtration
Does diffusion happen in all cells?
yes
True or False: all types of cells have a plasma membrane.
true
Does filtration happen in all cells?
only in certain cells
What is diffusion?
the random mixing of particles that occurs in a solution as a result of the kinetic energy of the particles
True or False: diffusion can happen with or without a cell membrane.
true
What happens in diffusion?
molecules move away from areas of higher concentration to areas where the concentration is lower; particles bump into each other which separates the higher concentration so that it spreads
In diffusion, molecules diffuse _______________ or ______________ their concentration gradient (high concentration to low concentration).
along or down
True or False: energy is not needed for diffusion.
true
What is a concentration gradient?
difference in concentration between two areas (between ICF and ECF)
The greater the difference in concentration between two areas the faster the ________________________________ of the particles, or the faster diffusion will happen.
net diffusion
What influences the speed of diffusion?
molecule size and temperature
Smaller molecules diffuse _________________ than large molecules.
faster
Diffusion eventually reaches _____________________ (evenly spread).
equilibrium
Cells don't _______________________ want to reach equilibrium.
always
Due to its _____________________ core, the _____________ ___________________ is a physical __________________ to free diffusion.
hydrophobic; plasma membrane; barrier
Anything with a _________________ or _________________ ___________________ ______________ don't permeate easily.
charge; polar covalent bonds
What are the types of diffusion?
simple diffusion, facilitated diffusion (via a carrier or channel), osmosis
All types of diffusion are ____________________ transport.
passive
What is simple diffusion?
unassisted diffusion of lipid-soluble, nonpolar or very small particles
What can pass through the membrane with simple diffusion?
oxygen, carbon dioxide, fat soluble vitamins, and steroid hormones
What type of protein is a channel?
integral transmembrane protein
What is an aqueous pore?
water-filled pore
How does a channel work?
transports a substance through an aqueous pore from one side of the membrane to the other
Substances are always moving ______________ their concentration gradient (high to low) through a channel.
down
Channels are __________________; each channel is specific for a particular __________.
selective; ion
What are the two types of channels?
leakage channels and gated channels
Which type of channels are always open?
leakage channels
Gated channels are . . .
closed most of the time, triggered to open for a very brief amount of time
How do chemically gated channels open?
from a chemical
How do mechanically gated channels open?
from mechanical pressure
How do voltage gated channels open?
when the charge changes
How can channels be inhibited?
by removing/adding channels
What is facilitated diffusion via a carrier?
a transmembrane integral protein that moves substances that are too large to pass through a channel
Facilitated diffusion via a carrier functions like a _____________________ __________.
revolving door
Carriers are ____________________ and can show ______________________.
selective; saturation
The rate of facilitated diffusion is ____________________ because permeability of membrane can be altered by changing the number of _______________________ ___________________________.
controllable; individual carriers/channels
What is osmosis?
diffusion of a solvent (water) through a selectively permeable membrane
Why can water cross the membrane?
it is small
What are aquaporins?
water specific channels of transmembrane proteins
When does osmosis occur?
whenever the water concentration differs on the two sides of the membrane
What is osmolarity?
the total concentration of all solute particles in a solution
Water moves ______________ water's concentration gradient (less concentration to high concentration), towards more solutes.
down
True or False: both passive and active transport happen in all types of cells.
true