Regenerative Neurobiology and Disease Lecture Notes

A collection of vocabulary flashcards based on key concepts from the lecture notes on regenerative neurobiology and diseases, focusing on neurodevelopmental disorders, epilepsy, and stem cell research.

Neurodevelopmental disorders

Characterized by an inability to reach cognitive, emotional, and motor developmental milestones.

Autism Spectrum Disorder (ASD)

A neurodevelopmental disorder that may exhibit various clinical signs and can co-occur with other disorders.

Epilepsy

A neurological condition characterized by recurrent seizures caused by brief disturbances in the electrical functions of the brain.

4E-BP2

A protein whose deletion results in lower epileptic seizure thresholds and increased seizure susceptibility.

Fragile X syndrome

A genetic disorder caused by >200 CGG repeats in the FMR1 gene leading to silenced transcription and absence of the Fragile X Mental Retardation Protein (FMRP).

G-banded analysis

A diagnostic method that uses Giemsa dye to stain chromosomes, enabling the detection of chromosomal abnormalities.

Stem cells

Cells that can differentiate into various specialized cell types, essential for regenerative medicine.

Adult neurogenesis

The process of generating new neurons from neural stem cells in the adult brain, significantly affected by various neuropsychiatric diseases.

CRISPR/Cas9

A gene-editing technology used to correct or introduce specific gene mutations.

Mesenchymal stem cells (MSCs)

Stem cells that can be isolated from various tissues and have neuroprotective actions through the secretion of factors.