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Vocabulary flashcards covering membrane structure, components, and transport processes from the lecture notes.
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Cell membrane
The boundary that defines the cell, formed by a phospholipid bilayer with embedded proteins and carbohydrates; regulates exchange with the environment.
Phospholipid bilayer
Two-layer structure that forms the core of the cell membrane; phospholipids have hydrophilic heads and hydrophobic tails.
Glycoprotein
Protein with carbohydrate attached; involved in cell signaling and cell-cell recognition.
Glycolipid
Lipid with carbohydrate attached; involved in cell recognition, signaling, and intercellular adhesion.
Integral membrane protein
Protein permanently associated with the membrane, often forming channels or transporters.
Peripheral membrane protein
Protein temporarily associated with the membrane, not embedded.
Cholesterol
A membrane lipid that buffers fluidity, preventing too much movement at high temperatures and too tight packing at low temperatures.
Phytosterols
Plant sterols (e.g., sitosterol, stigmasterol) that help maintain membrane fluidity and stability.
Amphipathic
Molecules with both hydrophilic (water-loving) and hydrophobic (water-fearing) regions.
Hydrophilic
Water-loving; polar region of a phospholipid head.
Hydrophobic
Water-fearing; nonpolar tail region of a phospholipid.
Polar head group
Hydrophilic head region of a phospholipid (phosphate-containing).
Glycerol backbone
The glycerol-derived backbone of phospholipids to which head group and tails attach.
Liposome
Spherical vesicle formed when phospholipids spontaneously assemble into a bilayer in water.
Fluid mosaic model
Model describing the membrane as a fluid, dynamic mosaic of lipids and proteins.
Osmosis
Diffusion of water across a semipermeable membrane toward higher solute concentration.
Isotonic
Solution with equal solute concentration to the cell's interior.
Hypotonic
Solution with a lower solute concentration outside than inside; water tends to enter the cell.
Hypertonic
Solution with a higher solute concentration outside the cell; water tends to leave the cell.
Diffusion
Movement of particles from high to low concentration due to random molecular motion.
Simple diffusion
Passive transport directly through the lipid bilayer, no proteins.
Facilitated diffusion
Passive transport via membrane proteins (channels or carriers); no energy required.
Channel protein
Transmembrane protein forming a pore for specific ions or molecules; may be gated (e.g., aquaporins for water).
Carrier protein
Transmembrane protein that binds a molecule and changes shape to shuttle it across.
Active transport
Movement of substances across the membrane using energy, usually against the concentration gradient.
Primary active transport
Direct use of ATP to power transport (e.g., Na+/K+ pump).
Sodium-potassium pump
A primary active transporter that pumps Na+ out and K+ in, maintaining gradients.
Secondary active transport
Uses electrochemical gradients created by primary active transport to move substances.
Electrochemical gradient
Combined chemical and electrical gradient used to drive transport.
Solution
Homogeneous mixture of solute and solvent; e.g., salt water.
Solute
Dissolved substance in a solution.
Solvent
Dissolving agent; typically water in biological systems.
Concentration gradient
Difference in solute concentration across space or a membrane; drives diffusion.
Cytoskeleton filaments
Internal protein filaments that anchor the membrane and support cell shape.
Aquaporin
Channel protein that specifically facilitates water movement across membranes.
Homeostasis
Maintenance of stable internal conditions by the cell.