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properties of muscle tissues
excitability
ability to respond to a stimulus
conductivity
ability to transmit electrical impulses along the cell membrane
contractibility
ability of a muscle to shorten
extensibility
ability of a muscle to lengthen (stretch!)
elasticity
ability of a muscle to return to its resting size after shortening or lengthening (bounce back to OG state)
muscle structural hierarchy
whole muscle
muscle fascicle
muscle fiber (muscle cells)
myofibrils
myofilaments
CT of skeletal muscle
endomysium
perimysium
epimysium
CT surrounding each individual muscle fiber
CT surrounding each fascicle
CT surrounding entire muscle
muscle attachments
tendon vs aponeurosis
CT that attaches muscle to something
broad flat sheet of CT (top of head or over abdomen)
sarcolemma
plasma membrane
sarcoplasm
cytoplasm
T-tubules
holes in sarcolemma that extend into sarcoplasm
carry impulses from sarcolemma to help stimulate muscle contraction
sarcoplasmic reticulum
right next to T-tubules
stores calcium and releases it
myofibrils
shorten which results in contraction of the muscle fiber
contain myofilaments= thick and thin
thick filaments
myosin
myosin heads
binding site for actin (they are mobile)
thin filaments
tropomyosin vs troponin
actin
covers the myosin binding sites
has calcium binding site
sarcomere
contains overlapping thick and thin filaments
one sarcomere spans from one Z DISC to the next
Z disc=borders of sarcomere
I band
contains ONLY thin filaments
A band
H zone vs M line
anywhere with thick filament (can overlap with thin)
ONLY where there is thick
center of the H zone (midline of sarcomere)
neuromuscular junction
between neuron and muscle fiber
components of neuromuscular junction
synaptic knob
expanded tip of neuron axon
synaptic vesicle
membrane sacs in synaptic knob filled with ACh
synaptic cleft
narrow SPACE separating synaptic knob and motor end plate
motor end plate
region of sarcolemma under synaptic knob
ACh receptors
proteins that bind ACh on the motor end plate
AChE
enzyme in synaptic cleft that breaks down ACh (prevents continuous stimulation of muscle)
muscle contraction
a nerve impulse causes Ach to be released in the synaptic cleft
it binds to receptors on motor end plate initiating a muscle fiber impulse
spread of impulse down T-tubules causes CA+ to leak into sarcoplasm
CA+ binds to troponin which exposes tropomyosin then myosin heads bind to actin's active sites
myosin pulls actin toward center of sarcomere and repeats
when impulse stops the CA+ goes back to sarcoplasmic reticulum, tropomyosin re-covers active sites, and the filaments slide back to their relaxed state
motor unit
a single motor neuron and the muscle fiber it controls
very specific only same type of fibers
Type 1
slow twitch fibers
smallest
aerobic
many mitochondria
Type 11a
intermediate
Type 11b
largest
anaerobic
fast twitch
a skeletal muscle contains ALL three fiber types but a motor unit can only contain ONE
muscle hypertrophy vs muscle atrophy
increases fiber size
decrease in size
muscle tone
constant tension even at rest
isometric vs isotonic
not changing in length (hold dumbells at 90 degrees)
muscles are changing in length
types of isotonic
concentric contraction vs eccentric contraction
muscle decreases in length
muscle is lengthening
agonist vs antagonist vs synergist
the main muscle producing movement
opposing muscle
helper muscle
fibromyalgia
unexplainable chronic muscle pain
muscular dystrophy
inherited disease with progressive deterioration of muscle tissue
myasthenia gravis
autoimmune disease
stops pathway from neuron to muscle fiber
cramps
involuntary pain
sustained contractions of a muscle
attachment of muscles of the head and neck
most attach to skull or hyoid bone
muscles of mastication
temporalis
masseter
attachments of sternocleidomastoid
attaches to the sternum
clavicle
mastoid process
erector spinae
3 groups
muscles help determine posture
iliocostalis (most lateral)
longissimus (intermediate)
spinalis (medial)
muscles involved with inhalation and exhalation
external intercostals
internal intercostals
diaphragm
diaphragm
most important muscle for breathing
dome shaped with a central tendon
muscles that move the glenohumeral joint
biceps brachii
deltoid
coracobrachialis
triceps brachii
teres major
lats
pectoralis major
rotator cuff muscles
subscapularis
supraspinatus
infraspinatus
teres minor
SITS
elbow flexors
biceps brachii
brachialis
brachioradialis
elbow extensors
triceps brachii
anconeus
flexor retinaculum
sheet of CT on wrist
carpal tunnel
space between carpal bones and flexor retinaculum
hip flexor muscles
iliacus
psoas major
sartorius
rectus femoris
muscles in the medial compartment of the thigh
adductor longus
pectineus
adductor brevis
gracilis
adductor magnus
muscles in the lateral compartment
tensor fascia latae, attaches to the iliotibial tract (band)
muscles of the posterior compartment that extend the thigh
biceps femoris
semimembranosus
semitendinosus
muscles of the anterior compartment that extend the knee
(called the quadriceps femoris)
rectus femoris
vastus lateralis
vastus medialis
vastus intermedius
CNS
brain and spinal cord
protected by skull and vertebral canal
responds to signals
PNS
detects changes
structure outside of CNS
cranial nerves, spinal nerves, ganglia
sensory nervous system
detects stimuli and transmits information from receptors to the CNS
somatic sensory vs visceral sensory
sensory input that is consciously perceived (eyes)
sensory input that is not consciously perceived (heart)
motor nervous system
initiates and transmits information from the CNS to the effectors
somatic vs autonomic motor
motor output that is voluntary/conscious
motor output that is involuntary/unconscious
neurons vs glial cells
transfer information (nerve cells)
support and protect neurons
axon hillock
region where the axon connects to the cell body
unipolar
single, short fiber branches like a T off of the axon
bipolar
2 processes and one axon
multipolar
many axons and a single cell body
neuroglia
(glial cells)
found in both CNS and PNS
capable of mitosis (neurons can't)
astrocytes
star shaped
help to form blood-brain barrier
prevents substances from entering CNS
supports doesn't send signals!
ependymal cells
line ventricles and help produce cerebrospinal fluid
microglia
immune cells
engulf debris
oligodendrocytes
CNS axons ONLY
wrap themselves around axons (spiders)
produce myelin
crucial with speed of neuron
satellite cells
regulate fluid around neuron cell bodies
schwann cells
PNS axons ONLY
not a spider
form myelin
saltatory conduction
an impulse jumps from one neurofibril node to another (the part where there is no myelin surrounding the axon)
continuous conduction
unmyelinated axons where the impulse doesn't jump it just goes straight through
nerve
bundle of neurons
3 types of CT around nerves
endoneurium
perineurium
epineurium
innermost (surrounds each axon)
surrounds each fascicle
surround the entire nerve
neuron pools
neurons that are grouped
many types that serve different functions
multiple sclerosis
autoimmune disease where the body attacks the myelin sheath
ALS
neurodegenerative disease affecting motor neurons
leads to atrophy
brain
gray matter vs white matter
most superficial (cerebral cortex)
myelinated & deep to gray matter
meninges
CT layers
-Epidural space
Dura mater
-subdural space
Arachnoid mater
-subarachnoid space-contains CSF
Pia mater- directly connected to surface of brain and spinal chord
dura mater
arachnoid mater
pia mater
most superficial (tough/strong)
spider web
thinnest and deepest, directly on the top of cerebral cortex
ventricles
cavities within the brain that contain cerebrospinal fluid
choroid plexus
produce and secrete CSF
functions of the CSF
buoyancy
protection
environmental stability (transports nutrients, removes waste from the brain)
blood brain barrier
regulates what substances can enter the brain
corpus callosum
connects the two hemispheres
broca's area vs wernicke's
motor speech
speech comprehension
Function of
frontal
parietal
temporal
occipital
insula
cognitive functioning and voluntary movement
sensory information
hearing
vision
taste & autonomic nervous system
primary motor cortex
in precentral gyrus
primary sensory cortex
in postcentral gyrus
diencephalon
relay station
epithalamus
thalamus
hypothalamus
epithalamus
pineal gland= secretes melatonin
habenular nuclei= visceral and emotional responses to odor
thalamus
relay center
Structure below hypothalamus
infundibulum= connects the pituitary gland and hypothalamus
brainstem
connects forebrain and cerebellum to spinal cord
midbrain
pons
medulla oblongata