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Achromatic granules
Granules that are not stained
Chromatic granules
Granules that are stained
Entamoeba histolytica
Small, discrete, usually central, with a bull's eye
karyosome; fine, uniform, evenly distributed granules;
may ingest RBC
Entamoeba dispar and Entamoeba harmanni
Small, discrete, usually central, with a bull's eye
karyosome; fine, uniform, evenly distributed granules;
may ingest Bacteria
Entamoeba coli
Large, eccentric; coarse, irregular; may contain
Bacteria, yeast, and other materials
Endolimax nana
Large and irregular (blot-like);
may contain Bacteria
Iodamoeba butschlii
Central or peripheral karyosome surrounded by achromatic granules;
may contain Bacteria, yeast, and other materials
Entamoeba gingivalis
Central and distinct karyosome;
may contain food vacuoles and WBCs