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CI:
angioedema or history of hereditary or idiopathic angioedema
Pregnancy
ACEi/ARB
Precaution:
Dehydration/ Volume depletion
Breastfeeding
ACEi/ARB
CI: dialysis
SGLT2i
Precautions:
Volume depletion
Pregnancy (2nd/3rd trimester)
Breastfeeding
SGLT2i
CI:
Hyperkalemia, Addison’s disease (spiro)
Aldosterone Antagonist
Precautions:
Pregnancy (spiro), Breastfeeding (both), use with caution in patients with low eGFR
Aldosterone Antagonist
CI:
Heart failure
concurrent beta blockers
Non-Dihydropyridine CCBs