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Epinephrine
α1, α2, β1, β2 agonist | Anaphylaxis, cardiac arrest, asthma | Tachycardia, hypertension | Low dose = β effects; high dose = α effects
Norepinephrine
α1, α2, β1 agonist | Septic shock | Reflex bradycardia, hypertension | Strong vasoconstrictor → ↑ SVR
Isoproterenol
β1, β2 agonist | Bradyarrhythmias | Tachycardia, hypotension | No α activity → ↓ diastolic BP
Dobutamine
β1 > β2 agonist | Acute heart failure, cardiogenic shock | Tachycardia | ↑ cardiac output with minimal SVR change
Dopamine
D1 → β1 → α1 (dose dependent) | Shock, HF | Arrhythmias | Low dose = renal vasodilation (classic Step pearl)